UNIVERSITAS AIRLANGGA



Detail Article

Berkala Ilmiah Kimia Farmasi

ISSN 2302-8270

Vol. 3 / No. 1 / Published : 2014-06

Order : 7, and page :42 - 47

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Original Article :

Prospektif kombinasi susu probiotik lactobacillus acidophilus dan bifidobacterium bifidum sebagai sediaan anti diare

Author :

  1. Rohdiya Wahyuni*1
  2. Isnaeni*2
  3. Asri Darmawati*3
  1. Mahasiswa Fakultas Farmasi
  2. Dosen Fakultas Farmasi
  3. Dosen Fakultas Farmasi

Abstract :

In the course of our screening program for anti diarrheal bacterial – Escheria coli, Salmonella typhimurium, and Vibrio cholerae agents from fermented probiotic milk, Lactobacillus acidophilus FNCC-0051 and Bifidobacterium bifidum as a potential probiotic were picked out for further investigation. Each probiotic microorganism was prepared as fermented milk by using 15% skim milk. Inhibition potency of the fermented milk that consisted of both probiotic microorganisms at 1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, and 9:1 ratio was assayed against diarrheal causing bacteria. The combination of two fermented probiotic milk showed strong inhibition against test bacteria at ratio of 4:6 and the MIC is 30%. On the other hands, total plate count of the combination is 108cfu/mL, is comply with the requirement for intestine as target side of action. Thus, the combination was considered of great potential to develop as an anti diarrheal preparation.    

Keyword :

Lactobacillus acidophilus, Bifidobacterium bifidum, anti-diarrhea, probiotik, fermented milk,


References :

Gomes A M P, dan Malcata F X,(1999) Bifidobacterium spp. and Lactobacillus acidophilus: biological, biochemical, technological and therapeutical properties relevant for use as probiotics Journal : Trends in Food Science & Technology

Ahmed FE,(2003) Genetically modified probiotics in foods Journal : Trends Biotechnol





Archive Article

Cover Media Content

Volume : 3 / No. : 1 / Pub. : 2014-06
  1. Penentuan Kemurnian Adenovirus Menggunakan Kromatografi Cair Kinerja Tinggi
  2. Validasi Metode Headspace-gas Chromatography-mass Spectrometry Untuk Analisis Multiresidu Pestisida Organofosfat Pada Sayuran
  3. Penggunaan Zat Pendestruksi Pada Cara Wet Ashing Untuk Analisis Timbal Dalam Sari Buah Kaleng Dengan Metode Spektroskopi Absorpsi Atom
  4. Aktivitas Antimikroba Dan Analisis Klt-densitometri Metabolit Fraksi –fraksi Ekstrak Endofit Dari Aglaia Odorata
  5. Pengaruh Ph Eluen Terhadap Hasil Desalting Crude Pertussis Toxin (pt) Dan Filamentous Hemagglutinin (fha) Dari Bordetella Pertussis
  6. Daya Hambat Kombinasi Susu Probiotik (lactobacillus Acidophilus + Lactobacillus Bulgaricus) Dan Pasta Tomat Terhadap Escherichia Coli Dan Staphylococcus Aureus
  7. Prospektif Kombinasi Susu Probiotik Lactobacillus Acidophilus Dan Bifidobacterium Bifidum Sebagai Sediaan Anti Diare

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