Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN 0854-4263
Vol. 16 / No. 2 / Published : 2010-03
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Original Article :
Analysis of eosininophil on acute interstitial nephritis
Author :
- Yedid Lebang*1
- Sulina Yanti Wibawa*2
- Mansyur Arif*3
- Departemen Patologi Kinik FK - UNHAS - RS. Dr. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan Km 10 Talamarea Makassar
- Departemen Patologi Kinik FK - UNHAS - RS. Dr. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan Km 10 Talamarea Makassar
- Departemen Patologi Kinik FK - UNHAS - RS. Dr. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan Km 10 Talamarea Makassar
Abstract :
Acute Interstitial Nephritis (AIN) is the main cause of acute renal failure because of hypersensitivity to many antibiotics and other drugs that potent to induce allergic response in renal interstitial tissue. Gold standard for AIN diagnosis upheld from clinical sign, laboratory, USG, Gallium renal tests and renal biopsy. A cross sectional study was carried out among 120 (AIN) patients and none (AIN) from the Paediatrics and Internal Medicine Department Wahidin Sudirohusodo hospital from June until September 2008. Eosinophil count was performed using haematology auto analyser. The data was analyzed by Mann-Whitney test using SPPS for windows. The total 120 samples consisted of 60 samples of AIN and 60 samples Non AIN were included in this study. Mean eosinophil in AIN 4. 9 % and non AIN 3. 1%. There were statistical difference of eosinophil level between AIN and non AIN with p < 0. 00. Eosinophil level can be used to differentiated between AIN and non AIN in conjunction to the clinical sign.
Keyword :
Eosinophil, Acute Nephritis Interstitial,
References :
Widiana IGR,(2006) Penyakit tubulointerstitial nephropathies Jakarta : Pusat penerbitan dep ilmu penyakit dalam FK UI
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