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Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 15 / No. 3 / Published : 2009-07

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Original Article :

Cd4 cell counts with igm herpes simplex-type 2 in hiv patients

Author :

  1. Bastiana*1
  2. Endang Retnowati K*2
  3. Erwin A Triyono*3
  1. Departemen Patologi klinik, FK UNAIR/RSU Dr. Soetomo, Surabaya
  2. Departemen Patologi Klinik FK Universitas Airlangga – RSUD Dr. Soetomo Jl. Prof. Mayjen Moestopo 6-8 Surabaya
  3. Unit HIV/AIDS, RSU Dr. Soetomo/Departemen Penyakit Dalam, FK UNAIR, Surabaya

Abstract :

Herpes simplex type-2 (HSV-2) infection is usually transmitted sexually and can cause recurrent, painful genital ulcers. Seropositivity of IgM HSV-2 indicates acute infection of HSV-2. The low level of CD4 cell counts can lead to opportunistic infection in HIV patients. Therefore, the aim of this study is to investigate the association between CD4 cell counts and HSV-2 infection (based on seropositivity of IgM HSV-2) in HIV patients with heterosexual risk factor in Dr. Soetomo Hospital, Surabaya. Specimens were collected during the first presentation on June and July 2008. HSV-2 IgM and was assessed by an ELISA technique using Herpelisa 2 IgM (recombinant) reagent, whereas CD4 cell counts was assessed by a Flowcytometry BD FACSCaliburTM System. The seropositivity of IgM HSV-2 in HIV persons 18 years of age or older was 27.3% (9/33). Median CD4 cell counts the number were 50 cells in μl. Persons with seropositive HSV-2 who had CD4 cell counts < 200 cells/μL and > 200 cells/μL were 66.6% (6/9) and 33.3% (3/9), respectively. Using chi square test, there was no association between CD4 cell counts and seropositivity of IgM HSV-2 in HIV patients. The seropositivity of IgM HSV-2 in HIV patients with heterosexual risk factor in Dr. Soetomo Hospital was 27.3%. There was no association between CD4 cell counts and the seropositivity of IgM HSV-2 in HIV patients with heterosexual risk factor.

Keyword :

Herpes simplex type-2, Human immunodeficiency Virus, CD4 cell counts,


References :

  1. Nasronudin, (2007). Penatalaksanan koinfeksi penderita HIV. Surabaya : Airlangga University Press


   


Archive Article

Cover Media Content

Volume : 15 / No. : 3 / Pub. : 2009-07
  1. Cd4 cell counts with igm herpes simplex-type 2 in hiv patients
  2. The transferrin saturation profile among anaemic blood donors
  3. Iron deficiency anemia of babies
  4. Patients’ serum protein electrophoresis with normal serum total protein level
  5. Inflammatory marker hs crp with hipertension
  6. Comparison of kalium serum level with or without insulin therapy at type 2 diabetic mellitus patiens
  7. Microalbuminuria of type 2 dm patients
  8. Analysis of the immunochromatography and enzyme-linked immunosorbent assay tests to diagnose helicobacter pylori in dyspepsia
  9. Soluble transferrin receptor level in human immunodeficiency virus/acquired immunodeficiency syndrome patients with anemia
  10. Comparison of specthrophotometer method with hemocue method for haemoglobin measurement in leucocytosis sample
  11. Toll-like receptor (tlr) and natural immunity
  12. A retinoid acid receptor in acute promyelocytic leukemia auer rods
  13. Errors during clinical laboratoric procedures