Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN 0854-4263
Vol. 14 / No. 3 / Published : 2008-07
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Original Article :
Cd4 examination and its correlation with hiv diseases stadium of patients
Author :
- Adi K. Aman*1
- Tonny*2
- Rachmad*3
- Installation/Department of Clinical Pathology Medical faculty University of North Sumatra/H. Adam Malik General Hospital
- Installation/Department of Clinical Pathology Medical faculty University of North Sumatra/H. Adam Malik General Hospital
- Special Centre Service, H. Adam Malik General Hospital Medan
Abstract :
The accurate measuring CD4 are important for knowing immune system from HIV infected person. Because there are increasing clinical complication with decreasing of CD4. Measuring of CD4 also useful for the decisions when therapy of ART started and monitoring efficacy of the medication. Also it is necessary to know CD4 and its relations to HIV stadium in HIV positive patients at Adam Malik General Hospital Medan. The CD4 examination used in EDTA blood. Immunophenotyping examination carried out by Flow Cytometry BD FACS CaliburTM used TritestTM BD reagent CD3/CD4/CD45 without true count tube. From 515 HIV patients, 80.5% are men, 86% from all patients between 20-40 years old with biggest risk factor are heterosexual. From 250 patients that examination of CD4, 81% patients are stadium I had amount CD4 > 350/mm3 and patients stadium III had amount CD4 < 200/mm3. Examination of CD4 are the important parameter to follow up condition of HIV patient for prevented not become worse, also knowing diseases progressivism and therapy progress.
Keyword :
CD4, flow cytometry, ART,
References :
Siregar F,(2004) AIDS dan penanggulannganya di Indonesia Medan : FKM USU
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