Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN 0854-4263
Vol. 13 / No. 2 / Published : 2007-03
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Original Article :
Congenital rubella syndrome based on serologic and rna virus examination
Author :
- Kadek -*1
- S Darmadi*2
- Bagian Patologi Klinik FK UNAIR/RSU Dr Soetomo Surabaya
- Bagian Patologi Klinik FK UNAIR/RSU Dr Soetomo Surabaya
Abstract :
Rubella infection with occurs during pregnancy, especially during the first trimester often caused by Congenital Rubella Syndrome (CRS). CRS can resulting abortions, miscarriages, stillbirth, and severe birth defects. The baby diagnosed with CRS when characterized by signs or symptoms from the following two categories A (Cataracts/congenital glaucoma, congenital heart disease (most commonly patent ductus arteriosus or peripheral pulmonary artery stenosis), loss of hearing, pigmentary retinopathy) or one categorie A and one catagorie B (Purpura, splenomegaly, jaundice, microencephaly, mental retardation, meningoencephalitis, radiolucent bone disease. Laboratory confirmation can be obtained by any of the following: virus isolation, serologi test (pasif hemaglutination, latex agglutination test, hemaglutination inhibisi, Flouresence immunoassay, Enzyme immunoassay), RNA test.
Keyword :
congenital Rubella Syndrome, serologic examination, RNA virus examination,
References :
Handojo I,(2004) Imunoasai Untuk Penayakit Infeksi Virus Surabaya : Airlanggang University Press
Matuscak R,(1990) Rubelola Virus Infection and Serology Philadhelpia : JB. Lipincott Co
Mahony JB, Chernesky MA,(2002) Rubella Virus Washington DC : American Society of Microbiology
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