UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 12 / No. 1 / Published : 2005-11

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Original Article :

Cushing syndrome in pregnancy

Author :

  1. Yetti Hernaningsih*1
  2. Sidarti Soehita*2
  1. Bagian Patologi Klinik Fakultas Kedokteran Unair/RSU Dr.Soetomo Surabaya
  2. Bagian Patologi Klinik Fakultas Kedokteran Unair/RSU Dr.Soetomo Surabaya

Abstract :

A 32 years old woman, pregnant 24-25 weeks, was admitted to the hospital with complaints of weakness, 6 years amenorrhoe,bruises on the skin and hair loss. Physical examination showed full moon face, buffalo hump, striae lividae, and echymosis.She was diagnosed as Cushing Syndrome with possible etiology adrenal tumor based on laboratory results: glucose intolerance,hypokalemia, increament of plasma cortisol before and after dexamethason supression tests (1352 and 1297 nmol/l), also decreementof plasma ACTH (5 pg/ml). During 22 days hospitalization, the patient’s condition became worse (heart failure, sepsis and shock)

Keyword :

cushing syndrome, cortisol, ACTH,


References :

Pudek,(1996) Adrenal Hormones and Hypertension. In:Kaplan LA, Pesce AJ (eds.). Clinical Chemistry, 3rd ed. St. Louis : Mosby

Abraham,(2003) Adrenal Disease and Pregnancy. http://www.emedicine.com/med/topic3266.htm, last updated:January 29. - : -

Demers,(2001) Adrenocortical Function. In:Burtis CA, Ashwood ER (eds). Tietz Fundamentals of Clinical Chemistry, 5th ed. Philadelphia : W.B. Saunders Company

Whitley,(2001) Adrenocortical Function. In:Burtis CA, Ashwood ER (eds). Tietz Fundamentals of Clinical Chemistry, 5th ed. Philadelphia : W.B. Saunders Company

Findling,(2001) Diagnosis and Differential Diagnosis of Cushing’s Syndrome. Endocrinology and Metabolism Clinics 30(3). - : -

Raff,(2001) Diagnosis and Differential Diagnosis of Cushing’s Syndrome. Endocrinology and Metabolism Clinics 30(3). - : -

Harris,(2002) Hypertensive Endocrine Disorders. Clinics in Family Practice 4(3). - : -

Fawcett,(2002) Hypertensive Endocrine Disorders. C



Archive Article

Cover Media Content

Volume : 12 / No. : 1 / Pub. : 2005-11
  1. The Microbiology Of Upper Respiratory Tract Infection On Surabaya’s Pilgrim Group 2004
  2. Determination Of Iron Deficiency In Chronic Disease Anemia By The Role Of Stfr-f Index
  3. Molecular Pathology Of Cerebrovascular Atherosclerosis
  4. Hypocolemic Periodic Paralysis
  5. Widal Tube Test Capability Using Imported Antigens And Local Antigens
  6. Increasing Quality Of Hospital Clinical Laboratory
  7. Cushing Syndrome In Pregnancy
  8. Hepatotoxic Effect Of Antituberculose Drugs On Aspartate Amino Transferase And Alanine Amino Transferase Levels In Tuberculosis Patients

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