Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN 0854-4263
Vol. 16 / No. 1 / Published : 2009-11
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Original Article :
Diagnostic value of malaria antigen cassette on malaria disease
Author :
- Binawati*1
- Prihatini*2
- M.Y Probohoesodo*3
- Departemen Patologi Klinik Fakultas Kedokteran Universitas Airlangga - RSUD Dr. Soetomo Surabaya
- Departemen Patologi Klinik FK Universitas Airlangga – RSUD Dr. Soetomo Jl. Prof. Mayjen Moestopo 6-8 Surabaya
- Departemen Patologi Klinik FK Universitas Airlangga – RSUD Dr. Soetomo Jl. Prof. Mayjen Moestopo 6-8 Surabaya
Abstract :
Malaria is an endemic disease in many countries. In 103 endemic countries with around 2.5 billion population, 1−3 million death cases were reported every year. Clinical criteria and blood smear established the diagnosis of malaria. ICT (imuno chromatography test) is needed in peripheral areas where there are no experienced laboratory technicians. The procedure is simple, practical, easy, as well as quicker than the conventional method, and no experienced technicians are needed this ICT advantages. The aim of this study is to know the diagnostic value of Malaria Antigen Cassette with microscopic examination as the gold standard examination of malaria. This research used observational cross-sectional method This study was done in Nusa Tenggara Barat during May−June 2008. Blood samples were taken by finger prick in patients with Malaria symptoms: fever, chill and sweating, followed by examining the blood smear by Malaria Antigen Cassette from Focus Diagnostic. The diagnostic value was then evaluated by calculating the sensitivity, specificity, positive predictive value as well as the negative predictive value. The diagnostic value of Malaria Antigen Cassette in patients with malaria falciparum was found as follows: sensitivity 95.2%, specificity 100%, positive predictive value 100%, and negative predictive value 97.6%. The diagnostic value of Malaria Antigen Cassette in patients other types than malaria falciparum was as follows: sensitivity 94.8%, specificity 100%, positive predictive value 100%, and negative predictive value 95.3%. The diagnostic value of Malaria Antigen Cassette was very high in diagnosing malaria falciparum compared to other types than malaria falciparum.
Keyword :
Malaria, malaria antigen cassette,
References :
White NJ, Breman JG,(1994) Malaria and Babesiosis New York : Mc Graw Hill
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