UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 12 / No. 2 / Published : 2006-03

Related with : Scholar   Yahoo!   Bing

Original Article :

Drug resistance of mycobacterium tuberculosis

Author :

  1. A. Nikmawati*1
  2. Windarwati*2
  3. Hardjoeno*3
  1. Alamat kantor: 1. Unit Pelayanan Laboratorium RS Wahidin Sudirohusodo Jl Perintis Kemerdekaan Km 10. Makassar Telp 0411-582678 2. Bagian Patologi Klinik Fakultas Kedokteran Unhas Jl Perintis Kemerdekaan Km 10. Makassar Telp 0411-586010
  2. Alamat kantor: 1. Unit Pelayanan Laboratorium RS Wahidin Sudirohusodo Jl Perintis Kemerdekaan Km 10. Makassar Telp 0411-582678 2. Bagian Patologi Klinik Fakultas Kedokteran Unhas Jl Perintis Kemerdekaan Km 10. Makassar Telp 0411-586010
  3. Alamat kantor: 1. Unit Pelayanan Laboratorium RS Wahidin Sudirohusodo Jl Perintis Kemerdekaan Km 10. Makassar Telp 0411-582678 2. Bagian Patologi Klinik Fakultas Kedokteran Unhas Jl Perintis Kemerdekaan Km 10. Makassar Telp 0411-586010

Abstract :

Patients infected with resistant Mycobacterium tuberculosis strain will be very difficult to cure by standard treatment. To evaluate the drug resistance of Mycobacterium tuberculosis. A Cross sectional study was performed from January until July 2005. Samples were obtained from sputum of the suspect tuberculosis. All samples were cultured in Lowenstein-Jensen Media and followed by sensitivity test according to resistance ratio method. Of 236 samples, there were 30% positive cultures. The percentage of mono-resistance to Isoniazid was 70%, to Rifampicin 64.3%, to Ethambutol 62.8% and Streptomycin 64.3%. The percentage of Multi Drug Resistant Tuberculosis (MDR-TB) was 20–40% and the percentage of poly-resistant (Ethambutol and Streptomycin) was 47.1%. The percentage of suspect tuberculosis with positive culture was 30%. There were also found high percentage of mono-resistant, poly-resistant and MDR-TB.

Keyword :

mycobacterium tuberculosis, tuberculosis, mono-resistant, poly resistant, MDR-TB,


References :

,(2002) Departemen Kesehatan Republik indonesia. Pedoman Nasional
penanggulangan Tuberkulosis - : -

Simon,(2005) Management Issue in Tuberculosis in
the Asia-Pasific Region. Medical Progress. CMP Medica. - : -

,(2004) Ditjen PPM dan PL DEPKES. Penyakit Tuberkulosis. 2004.
http://www.penyakitmenular.info/pm/detil.aspm=0&I=273 - : -

Sandjaja,(1992) Isolasi dan Identifikasi Mikrobakteri. Widya
Medika. Jakarta - : -

Rosana,(2005) Multidrug-Resistant
Tuberculosis. Majalah Kedokteran Indonesia, Jakarta
- : -

Prawoto,(2005) Multidrug-Resistant
Tuberculosis. Majalah Kedokteran Indonesia, Jakarta
- : -

Sudiro,(2005) Multidrug-Resistant
Tuberculosis. Majalah Kedokteran Indonesia, Jakarta
- : -

Sudiro,(2005) Multidrug-Resistant
Tuberculosis. Majalah Kedokteran Indonesia, Jakarta
- : -





Archive Article

Cover Media Content

Volume : 12 / No. : 2 / Pub. : 2006-03
  1. The Manual And Automatic Tests Results Of Erythrocyte Sedimentation Rate
  2. Drug Resistance Of Mycobacterium Tuberculosis
  3. Analysis Of Acid Fast Bacilli (afb) Findings And Concentrated Slides In Suspected Tuberculosis
  4. The Microorganism Pattern In The Vagina Of Pregnancy Women In Dr. Soetomo Hospital Surabaya
  5. Collection And The Limit Time Of Using Diapers Samples For Urin Related Culture
  6. Laboratoric Diagnosis Of Avian Influenzae (h5n1)
  7. The Habitualis Abortion In Antiphospholipid Syndrome
  8. Evaluation Of Immunochromatography Method For Determination Of Immunoglobulin M And G Anti-dengue In Dengue Pediatric Patients)
  9. Quality Control In Clinical Microbiology
  10. Old People And Diabetes Mellitus
  11. The Analysis Of Serum Osteocalcin Level On Osteopenic And Osteoporotic Subjects

Information CPML