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Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 17 / No. 3 / Published : 2011-01

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Original Article :

Hematology test of dengue hemorrhagic fever on suspected patients indicated for hospitalization

Author :

  1. Juranah*1
  2. Darwati Muhadi*2
  3. Mansyur Arif*3
  4. Burhanuddin Bahar*4
  1. Bag PK FK-UNHAS Makassar
  2. Bag PK FK-UNHAS Makassar
  3. Bag PK FK-UNHAS Makassar
  4. Departemen Kesehatan Masyarakat Universitas Hasanuddin, Makassar

Abstract :

  Indonesia is an endemic area of Dengue Hemorrhagic Fever (DHF). The clinical symptoms of this  disease varies; it can be asymptomatic or atypical fever. Therefore, the early detection of Dengue virus is important to reduce the incidence of new victims from this infection. The aim of this study was to find out the haematological features of DHF suspected patients indicated for hospitalization. A cross-sectional study was done on DHF suspected patients indicated for hospitalization. The data were obtained from the Medical Record at Wahidin Sudirohusodo Hospital from January-July 2009. The data were presented in the form of table. The results showed that the mean leukocyte counts was 5.138 103/µL ranging from 2.10–16.70 103/µL, the mean erythrocyte count was 5.136 106/µL ranging from 3.2–6.40 106/µL, the mean platelet count was 111, 27 103/µL ranging from 11.40–260 103/µL. The DHF patients at admission who had leucositopenia, thrombocytopenia, and monocytosis were 54.30%, 71.40%, and 51.40%, respectively. Based on the result it can be concluded, that the most common haematological abnormality in DHF suspected patients whom indicated for hospitalization were thrombo cytopenia, leucocytopenia and monocytosis.       Indonesia merupakan wilayah endemik Demam Berdarah Dengue. Gejala klinis bervariasi, dapat bersifat tanpa gejala (asimtomatik) atau berupa demam yang tidak khas, oleh karena itu temuan dini infeksi virus dengue perlu diketahui untuk mengurangi korban akibat infeksi tersebut. Tujuan penelitian ini adalah untuk melihat gambaran uji hematologi pasien terduga Demam Berdarah Dengue (TDBD) indikasi rawat inap. Penelitian dilakukan secara potong silang (cross sectional) dilakukan di 35 hasil uji hematologi di pasien TDBD indikasi rawat inap, diambil dari Rekam Medik di Rumah Sakit Wahidin Sudirohusodo mulai Januari 2009-Juli 2009. Data disajikan dalam bentuk tabel. Hasil telitian menunjukkan jumlah rerata leukosit 5,138 103/µL dalam rentang 2,10-16,70 103/µL, jumlah rerata eritrosit 5,136 106/µL dalam rentang 3,23-6,40 106/µL, jumlah rerata trombosit 111,27 103/µL dari rentang 11,40-260 103/µL. Leukositopenia 54,30%, Trombositopenia 71,40% dan Monositosis 51,40%. Didasari telitian ini dapat disimpulkan bahwa kelainan hematologi terbanyak yaitu trombositopenia,  leukositopenia, dan monositosis terdapat di pasien TDBD, dan mereka diindikasikan untuk rawat inap.

Keyword :

haematological test, dengue haemorrhagic fever suspected patients, indication of hospitalization,


References :

  1. 1. Suhendro, Nainggolan L, Chen K, Pohan HT, (2007). Demam berdarah dengue. In: Buku Ajar Ilmu Penyakit Dalam. Jakarta : Pusat Penerbit Ilmu Penyakit Dalam FKUI
  2. 2. Lee MS, Hwang KP, Chen TC, Lu PL, Chen TP, (2006). Clinical characteristics of dengue and dengue hemorrhag ic fever in a medical center of southern Taiwan during the 2002 epidemic. Taiwan : In Journal of Microbiology, Immunology and Infection
  3. Gubler D J, (1998). Dengue dan dengue hemorrhagic fever. USA : Clinical Microbiology Reviews
  4. 4. Utama HW, Komalasari S, Ranika M, Yanti I, (2009). Program pemberantasan penyakit DBD di Puskesmas Sukarani Palembang thn 2004, 2005, 2006. Palembang : www.klikharrywordpress.com
  5. Menkes RI, (2008). Keputusan Menteri Kesehatan Republik Indonesia Nomor: 296/MENKES/SK/III/2008 tentang Pedoman Pengobatan Dasar Puskesmas Menteri Kesehatan Republik Indonesia. Jakarta : Menkes RI


   


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