UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 16 / No. 1 / Published : 2009-11

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Original Article :

Homolog legionella pneumophila distribution and nosocomial pneumopniae

Author :

  1. Noormartany*1
  1. Bagian Patologi Klinik Fakultas Kedokteran UNPAD – RSHS Bandung

Abstract :

L. pneumophila is one of the nosocomial pneumonia causes that contaminated hospital water distribution system. The aim of this study was to determine the homology between L. pneumophila 16S rRNA base sequence found in the water distribution system and the sequence derived from the sputum of nosocomial pneumonia patients identified at RSHS Bandung as well as the homology ofL. pneumophila 16S rRNA found in the same system network. The study also include the nosocomial pneumonia patients at RSHS Bandung with L. pneumophila from GenBank. The research using descriptive bioinformatics BLAST method by comparative analytic approach, which performed from April 2006 to February 2008. The material consists of 60 biofilm samples from water distribution system and pneumonia nosocomial patient’s sputum is positive L.pneumophila from water distribution system in her/his room. In the result was found: out of the 60 biofilm samples from the water distribution system, there are seven (7) L. pneumophila positive PCR and culture. During the 12 months of observation, there is only one (1) out of 31 pneumonia nosocomial patients with positivelyL. pneumophila PCR and culture. The conclusion so far can be mentioned that: The water distribution system in RSHS for patient rooms may become the source for nosocomial pneumonia transmission of L. pneumophila and also was detected a new species of L. pneumophila that is genetically different from that has been found in GenBank.

Keyword :

L. pneumophila, water distribution system, pneumonia patients, homology,


References :

PR Murray, KS Rosenthal, MA Pfallper,(2005) Legionella Philadhelpia : Elsiever Mosby





Archive Article

Cover Media Content

Volume : 16 / No. : 1 / Pub. : 2009-11
  1. Homolog Legionella Pneumophila Distribution And Nosocomial Pneumopniae
  2. Diagnostic Value Of Malaria Antigen Cassette On Malaria Disease
  3. Cd4 Analysis In Treatment Of Hiv-tb Co-infected Patients
  4. Analysis Of Uric Acid Level In Patients Of Carcinoma Mammae
  5. Anti Hcv And The Patient’s Prevalence Of Virus Hepatitis C Infection
  6. The Evaluation Of Transaminase Activities, And Bilirubin Level In Patients With Hepatitis B Virus And C Virus
  7. Correlation Degree Of Non-alcoholic Fatty Liver With Aminotransferase Serum Activity
  8. Accuracy Of Bactident Aminopeptidase Test In Identification Gram Negative Bactery)
  9. Study Of Cd38 Expression On Lymphocyte 8+, Cd4+ Profile, And Clinical State Immunological And Clinical State Profile Of Aids/hiv Patients With Antiretroviral Therapy)
  10. Eosinofil After Mucosal Nasal Brushing And Routine Hematology In Allergy Rhinitis
  11. Normoblast Counting Between Acute Myeloblast Leukemia And Acute Lymphoblastic Leukemia In Peripheral Blood Smear Of Patients
  12. Measurement And Clinical Application Of Thrombin Activatable Fibrinolysis Inhibitor
  13. Abnormal Trombosit In Post-partum
  14. Laboratory Costing Per Test Based On Jaros Ml Method

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