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Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 17 / No. 1 / Published : 2010-01

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Original Article :

Methicillin resistant on staphylococcus aureus at hospital ward

Author :

  1. Wildana*1
  2. Nurhayana Sennang*2
  3. Benny Rusli*3
  1. Bag PK FK-UNHAS Makassar
  2. Bag PK FK-UNHAS Makassar
  3. Bag PK FK-UNHAS Makassar

Abstract :

  Methicillin Resistant Staphylococcus Aureus (MRSA) is a major nosocomial pathogen worldwide. MRSA infection typically aggravates the patient condition. MRSA infection increases morbidity and mortality. The study was aimed to find out the MRSA occurrence in Dr. Wahidin Sudirohusodo Hospital Makassar patients during July 2008 – June 2009. A retrospective study was performed using data from the medical records including the results of culture and antimicrobial susceptibility test in Dr. Wahidin Sudirohusodo Hospital Makassar. Among 1082 results of the culture test, 5.2% were identified as Staphylococcus aureus, consist of 51.8% MSSA (Methicillin Sensitive Staphylococcus aureus) and 48.2% MRSA. Most of the MRSA patients were treated in orthopaedic surgery (30%), internal (22%), and paediatric (19%) wards. Based on the clinical conditions, most of the patients were in post surgery care (44.4%), pneumonia (18, 5%), and diabetic foot (7, 5%). All of the MRSA isolates were multiresistant (resistant to three or more antimicrobials) but 96% remain sensitive to vancomycin. It was concluded that most of MRSA patients were staying in the orthopaedic surgery ward. Based on this clinical condition, most of the patients were in the post surgery care. All of the MRSA isolates were multiresistant, but most of them remain sensitive to vancomycin.   Methicillin Resistant Staphylococcus Aureus (MRSA) merupakan patogen nosokomial utama di seluruh dunia. infeksi MRSA biasanya memperburuk kondisi pasien serta meningkatkan morbiditas dan mortalitas. Tujuan penelitian ini untuk mengetahui kejadian MRSA di RS Dr Wahidin Sudirohusodo Makassar, periode Juli 2008 - Juni 2009. Penelitian retrospektif dilakukan menggunakan data dari rekam medis termasuk hasil kultur dan uji kepekaan antimikroba di Rumah Sakit Dr Wahidin Sudirohusodo Makassar. Dari 1082 hasil kultur, ditemukan Staphylococcus aures sebanyak 5,2 % yang terdiri dari MSSA (Methicillin Sensitive Staphylococcus aureus) sebanyak 51,8 % dan MRSA 48,2%. Pasien MRSA terbanyak dirawat di ruang perawatan bedah orthopedi (30%), penyakit dalam (22%) dan perawatan anak (19%).  Berdasarkan keadaan klinik, terbanyak dirawat adalah pasien dengan tindakan operasi 44,4%, pneumonia (18,5%) dan kaki diabetik (7,5%). Semua isolat MRSA yang diuji adalah multiresisten (resisten terhadap tiga atau lebih antibiotik) tetapi 96% masih sensitif terhadap vankomisin.

Keyword :

Methicillin Resistant Staphylococcus aureus, antimicrobial susceptibility test,


References :

  1. Royal College of Nursing, (2005). Methicillin-resistant Staphylococcus aureus (MRSA). London : www.rcn.org.uk/mrsa
  2. Lowy FD, (2003). Antimicrobial Resistance: the Example of Staphylococcus aureus. USA : The Journal of Clinical Investigation
  3. Biantoro IK, (2008). Tinjauan Pustaka Methicillin-resistant Staphylococcus aureus (MRSA). Jakarta : www. scribd.com
  4. Turner JM, (2004). Diabetic MRSA Foot Infection – Role of Linezolid Therapy. USA : http://dvd.sagepub.com
  5. Klein E, Smith DL, (2009). Laxminarayan R. Hospitalizations and Deaths Caused by Methicillin-Resistant Staphylococcus aureus. USA : www.cdc.gov


   


Archive Article

Cover Media Content

Volume : 17 / No. : 1 / Pub. : 2010-01
  1. (urine eosinophyl in acute interstitial nephritis (ain)
  2. Methicillin resistant on staphylococcus aureus at hospital ward
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