UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 19 / No. 2 / Published : 2013-01

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Original Article :

Microbes and antimicrobial sensitivity in open fracture

Author :

  1. Yanty Tandirogang*1
  2. Tenri Esa*2
  3. Nurhayana Sennang*3
  1. Bag PK FK-UNHAS Makassar
  2. Departemen Patologi Klinik, Fakultas Kedokteran Universitas Hasanuddin, RS. Dadi Makassar
  3. Bag PK FK-UNHAS Makassar

Abstract :

About 70% of all nosocomial infections occur in surgical patients. In open fracture, there is contact with the environment or unsterile body compartment, so that bacterial contamination may occur and cause infection. Besides debridement, prophylactic antibiotics have been used as a standard procedure in the open fracture management. This procedure may cause antibiotics resistance leading to increase the number of infections. The aim of this retrospective study was to know the characteristics, microbial pattern, and sensitivity of 35 cultures and sensitivity test of open fracture patients in Orthopaedics Department of Wahidin Sudirohusodo Hospital during the period of June 2009–June 2010. The most common bacteria found were Proteus mirabilis (26%), Klebsiella pneumonia (14. 8%), and Providencia alcalifaciens (14%). The sensitivity test for antimicrobials showed that most of the 19 antimicrobials, were resistant. The sensitive antimicrobial is Meropenem.     Sekitar 70% dari seluruh infeksi nosokomial dilaporkan terjadi di penderita yang menjalani pembedahan. Dalam kasus patah tulang terbuka terjadi hubungan dengan dunia luar atau rongga tubuh yang tidak steril, sehingga mudah terjadi pencemaran kuman dan dapat menyebabkan komplikasi infeksi. Di samping pemotongan jaringan pengikat/penekan (debridement), penggunaan antibiotik profilaksis juga telah menjadi tatalangkah baku penanganan patah tulang terbuka. Hal ini memungkinkan resistensi antibiotik terjadi, dengan akibat angka infeksi meningkat. Penelitian ini dilakukan dengan retrospektif, bertujuan untuk mengetahui jenis kuman, dan kepekaan terhadap 35 hasil periksaan kultur dan uji kepekaan dalam nanah (pus) penderita patah tulang terbuka yang dirawat di Bagian Ortopedi RS Wahidin Sudirohusodo Makassar dalam masa waktu Juni 2009–Juni 2010. Hasil kultur kuman menunjukkan bahwa jenis yang terbanyak adalah Proteus mirabilis (26%), Klebsiella pneumonia (14,8%), dan Providencia alcalifaciens (14%). Hasil uji kepekaan terhadap antibiotik menunjukkan jumlah prosentase resistensi yang tinggi, yakni di atas 70%. Antibiotik yang masih peka hanya Meropenem.

Keyword :

Open fracture, microbes, antimicrobial sensitivity,


References :

Rasjad Ch, Trauma,(2000) Pengantar Ilmu Bedah Ortopedi Makassar : Bintang Lamumpatue

http://bedahugm.net,(2009) Fraktur Terbuka http://bedahugm.net : http://bedahugm.net

Kharisma, Ratih S,(2005) Studi Penggunaan Antibiotik Profilaksis Pada Bedah Orthopaedi Kasus Fraktur Terbuka Grade 2 dan Grade 3 Surabaya : Airlangga University Library

4. Seekamp A, Kontopp H, Schandelmaier P, Krettek Ch, Tscherne H,(2000) Bacterial Cultures and Bacterial Infections in Open Fractures Eropa : European Journal of Trauma

Hidajat NN,(2009) Pencegahan Infeksi Luka Operasi Bandung : FK-Unpad





Archive Article

Cover Media Content

Volume : 19 / No. : 2 / Pub. : 2013-01
  1. Clinical Manifestion Sepsis And Nitric Oxide Level On Mice Induced By Lipopolysaccharide
  2. Gandarusa (justicia Gendarussa Burm.f.) Water And Expression Of Hyaluronidase Gene By Pcr Analysis
  3. Proteinuria In Stroke With And Without Diabetic
  4. The Stewart’s Approach In Blood Ph Underlying Metabolic Acidosis
  5. Microbes And Antimicrobial Sensitivity In Open Fracture
  6. Katekin From Green Tea Leaves (camellia Sinensis) To Malondialdehyde (mda) And Super Oxide Dismutase (sod)
  7. Procalcitonin And Interleukin-6 In Sepsis Systemic Inflammatory Response Syndrome (sirs)
  8. Gram Negative And Gram Positive Aerobic Bacteria Identification Using Conventional And Automatic Method
  9. Immature Platelet Fraction (ipf) And Thrombopoietin In Liver Cirrhosis
  10. Eosinopenia And Procalcitonin In Sepsis
  11. C-x-c Receptor 4 (cxcr4) In Metastasis Of Breast Cancer
  12. Hairy Cell Leukaemia

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