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Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 13 / No. 1 / Published : 2006-11

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Original Article :

Microbial patterns based on type of spesimens and its sensitivity to antimicrobial drugs

Author :

  1. Rostina*1
  2. B Rusli*2
  3. Hardjoeno*3
  1. Bagian Patologi Klinik Fakultas Kedokteran Universitas Hasanudddin, RSUP DR. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan KM. 10, Makassar
  2. Bagian Patologi Klinik Fakultas Kedokteran Universitas Hasanudddin, RSUP DR. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan KM. 10, Makassar
  3. Bagian Patologi Klinik Fakultas Kedokteran Universitas Hasanudddin, RSUP DR. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan KM. 10, Makassar

Abstract :

High prevalence of infectious diseases in Indonesia lead to the use of uncontrollable anti microbial treatment with less concern to drug resistance, marked with fewer requests for sensitivity testing. This leads to irrational anti microbial treatment and increasing drug resistance. With unsupported condition for using a sensitivity test prior to anti microbial treatment, a common guide for choosing an anti microbial agent for infection of specific organ system is needed. A descriptive study of retrospectively collected data of sensitivity test results was done on 841 spesimens from sources of infected organs in Wahidin Sudirohusodo Hospital of Makassar during 2005–2006 periods. Objectives of this study are to know the microbial pattern of specific organ infection (represented by microbes of the specimens), antimicrobial sensitivity pattern of the microorganisms, and whether there is shifting of the pattern within a 1 year period. Shifting of microbial patterns during 2005–2006 period was found. Klebsiella aeroginosa, Enterobacter agglomerans, Alkaligenes faecalis and Escherichia coli were the most frequent micro organisms found from spesimens examined. Most of antimicrobial drugs commonly used were found effective to most of micro organisms, while amikacin, cefepime, gentamycin, sulbactam, tobramycin, vancomycin and meropene were still sensitive enough to the majority of the infectious agents.

Keyword :

Anti microbes, drug sensitivity pattern, drug resistance,


References :

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Archive Article

Cover Media Content

Volume : 13 / No. : 1 / Pub. : 2006-11
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