Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN 0854-4263
Vol. 20 / No. 1 / Published : 2013-01
Order : 5, and page :20 - 24
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Original Article :
Microrganisms and sensitivity tests of diabetic foot
Author :
- Ari Sutjahjo*1
- Dosen Fakultas Kedokteran
Abstract :
The purpose of this study was to know the bacterial pattern causing foot infections in diabetes mellitus (DM) patients and the sensitivity test results of the bacteria against various antibiotics that have been set. This research was conducted as a retrospective study using medical records. The study was carried out on diabetic foot patients of all In-patient Wards, Department of Internal Medicine, Dr. Soetomo Hospital, who met the inclusion criteria between January 1, 2003 up to December 31, 2007. The stages were classified according to the Wagner - Merrit criteria. Laboratory and clinical data were taken from the medical records of the patients who were admitted. Infected diabetic foot was found in 30.9% of patients. The causative bacteria consisted of : Pseudomonas (20.3%), Streptococcus (15.25), Klebsiella (13.9%), E.coli (12.6%), Proteus (12.6%), and Staphylococcus (11.3%). The Imipenem antibiotic showed the highest sensitivity (99.2%), followed by Norfloxacin (98.8%), Meropenem (98.2%), Ofloxacin (97.7%) and Cefuroxime (95.3). In this study, it was found that the most resistancy was to Erythromycin (46.3%) followed by Chloramphenicol (44.2%), Ceftazidime (41.1%), Cefotaxime (36.6%) and Ciprofloxacin (33.5%). It can be concluded that most of the bacteria causing the diabetic foot infections were Gram-negative aerobic bacterias and the highest sensitivity was to Imipenem, Norfloxacin, Meropenem as well as Cefuroxime. Tujuan penelitian ini adalah untuk mengetahui pola kuman penyebab infeksi kaki penderita diabetes melitus (DM) dan hasil uji kepekaan kuman terhadap berbagai antibiotik yang telah ditentukan. Penelitian ini dilakukan secara retrospektif terhadap keadaan penderita kaki diabetik (KD) yang rawat inap di semua Ruangan Penyakit Dalam SMF Ilmu Penyakit Dalam RSUD Dr. Soetomo Surabaya dan memenuhi patokan kesertaan antara tanggal 1 Januari 2003 sampai dengan 31 Desember 2007. Tahap KD digolongkan menurut patokan Wagner-Merrit. Data laboratoris dan klinis diambil dari catatan medik/DMK penderita saat MRS. Kaki diabetik terinfeksi (KDT) ditemukan di 30,9% penderita Bakteri penyebab KDT terbanyak adalah : Pseudomonas (20,3%), streptococcus (15,25%), Klebsiella (13,9%), E.coli (12,6%), Proteus (12,6%), dan Staphylococcus (11,3%). Antibiotika yang berkepekaan tertinggi adalah: Imipenem (99,2%), diikuti oleh Norfloxacine (98,8%), Meropenem (98,2%), Ofloxacine (97,7%)dan Cefuroxime (95,3%). Resistensi terbanyak didapat di Erithromycine (46,3%), Chloramphenicol (44,2%), Ceftazidime (41,1%), Cefotaxime (36,6%) dan Ciprofloxacin (33,5%). Dapat disimpulkan bahwa sebagian besar bakteri penyebab infeksi di KDT adalah bakteri aerob Gram negatif dan berkepekaan tertinggi terhadap Imipenem, Norfloxacine, Meropenem dan Cefuroxime.
Keyword :
Diabetic foot infection, sensitivity tests,
References :
Waspadji S,(2006) Kaki Diabetes Jakarta : Pusat penerbitan dep ilmu penyakit dalam FK UI
Archive Article
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Volume : 20 / No. : 1 / Pub. : 2013-01 |
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