UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 19 / No. 1 / Published : 2012-01

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Original Article :

Ovarian dysgerminomas cancer

Author :

  1. Hegaria Rahmawati*1
  2. Darmawaty ER*2
  3. R Pakasi*3
  1. Bag PK FK-UNHAS Makassar
  2. Bag PK FK-UNHAS Makassar
  3. Bag PK FK-UNHAS Makassar

Abstract :

Ovarian cancer is a female reproductive organ malignancy and the second most common gynaecological type cancers. World Health Organisation classifies ovarian cancer based on their origin: superficial stroma-epithelium tumour, cord-stroma sex tumour, and germ cell tumour originated from germinal cells (yolk sac). Epithelium type of ovarian cancer is common, while the germinal type is rare and can be found in teenagers and young women aged 16-20 years old. A case of suspected dysgerminomas ovarian cancer grade IIIA was reported in a 12 years old girl. The diagnosis was established by tumour markers, USG/CT Scan of abdomen, surgery, and frozen section evaluations. The reviewer expected better survival prognosis after surgery and three cycles of chemotherapy combinations were executed. The evaluations of when serial tumour markers CA-125 were suggested during chemotherapy to detect any recurrences factors possibility of the related cancer.     Kanker indung telur (ovarium) merupakan keganasan organ reproduksi perempuan dan merupakan jenis kanker tersering kedua dari seluruh kanker ginekologis. Penggolongan menurut World Health Organisation (WHO) untuk kanker ovarium dapat dibedakan berdasarkan asal jenis sel, yaitu tumor: stroma-epitel permukaan, seks cord-stromal dan sel benih (germ) yang berasal dari sel germinal (kantung kuning telur/yolk sac). Kanker ovarium jenis epitel sering ditemukan, sedangkan yang germinal jarang ditemukan dan dapat terjadi di remaja dan perempuan muda yang berusia antara 16-20 tahun. Satu kasus kanker ovarium yang terduga tumor sel benih (disgerminoma) tahap IIIA dilaporkan diidap anak perempuan usia 12 tahun. Diagnosis ditetapkan berdasarkan pemeriksaan: petanda tumor, USG/CT Scan Abdomen, pembedahan, dan potong beku. Pasien pengidap penyakit ini diharapkan dapat bertahan hidup karena telah dibedah yang dilanjutkan dengan kemoterapi gabungan tiga siklus. Disarankan pemeriksaan petanda tumor CA-125 secara berturut-turut selama kemoterapi untuk mengetahui respons saat pengobatan dan sesudahnya untuk menemukan kemungkinan ada faktor kekambuhan kanker terkait.

Keyword :

Ovarian cancer, germ cell tumour, dysgerminomas,


References :

Sahil MF,(2007) Penatalaksanaan Kanker Ovarium pada Wanita Usia Muda dengan Mempertahankan Fungsi Reproduksi Medan : FK-USU

Kumar V, Cotran RS, Robbins SL,(2007) Sistem Genitalia Perempuan dan Payudara. Dalam : Buku Ajar Patologi Jakarta : EGC

Kresno SB,(2011) Aspek Imunologi Kanker Ovarium. Dalam: Pendidikan Berkesinambungan Patologi Klinik 2011 Jakarta : Bagian Patologi Klinik FK UI

Oesman F,(2011) Biomarker Kanker Ovarium. Dalam: Pendidikan Berkesinambungan Patologi Klinik 2011 Jakarta : Bagian Patologi Klinik FK UI

Mitchell RN, et al,(2006) Traktus Genitalia Wanita. Dalam: Buku Saku Dasar Patologis Penyakit Jakarta : EGC





Archive Article

Cover Media Content

Volume : 19 / No. : 1 / Pub. : 2012-01
  1. Pulmonary Cryptosporidiosis In Hiv And Aids
  2. Aerob Bacteria And Antimicrobial Susceptibility
  3. Plasma Volume And Factor Viii In Cryoprecipitated
  4. Comparation Measurement Triglycerides, Glycerol Blanking And Non Glycerol Blanking In Liver Cirrhosis
  5. The Residue Of Leukocyte In Thrombocyte Concentrate
  6. Antimicrobial Sensitivity Of Blood Culture In Neonatal Sepsis
  7. Neutrophils Lymphocyte Ratio In Acute Appendicitis
  8. Curcuma Zedoaria And Morinda Citrifolia As Hepatoprotector Against Carbontetrachloride
  9. Mean Platelet Volume In Stroke
  10. Dengue Serotypes Distribution In Surabaya In The Year 2012
  11. M.tuberculosis In Innate Immunity Associated With The Receptors
  12. Ovarian Dysgerminomas Cancer
  13. Information System In Laboratory Services

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