UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 18 / No. 3 / Published : 2012-01

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Original Article :

Pulmonary cryptosporidiosis in tbc patients

Author :

  1. R. Heru Prasetyo*1
  1. Laboratorium Parasitologi Progam Studi D3 Analis Medis Fakultas Kedokteran Universitas Airlangga, Departemen Parasitologi Fakultas Kedokteran Universitas Airlangga, Lembaga Penyakit Tropis ( Institute of Tropical Disease ) Universitas Airlangga

Abstract :

      The pulmonary cryptosporidiosis cases had been reported for immunocompromised persons, most all of whom were secunder infected with HIV and AIDS patients. Tuberculosis is a chronic respirtory disease and tending to cause a weakened immune system (immunocompromised). However, pulmonary cryptosporidiosis has not been previously reported as secunder infection in tuberculosis patients. The objective of this study was to know the prevalence of pulmonary cryptosporidiosis determination in tuberculosis patients. This research was carried out by a cross sectional study utilitzing waste sputum samples from tuberculosis patients. The detection of Cryptosporidium oocyst used modified version acid fast stain of Ziehl Neelsen technique. Three sputum samples among 44 sputum samples (6.8%) had Cryptosporidium oocyst positive. These findings suggest that there was a potential for respiratory transmission of cryptosporidiosis. Although the prevalence of pulmonary cryptosporidiosis in tuberculosis patients are low, the researcher suggest that the possibility of pulmonary cryptosporidiosis as a secondary infection in tuberculosis patients existed, and there for a laboratory examination of pulmonary cryptosporidiosis becoming routinely laboratory for tuberculosis patients.             Beberapa kasus cryptosporidiosis paru sudah dilaporkan dapat terjadi di penderita dengan immunocompromised (penurunan kekebalan tubuh), hampir semua yang dilaporkan merupakan infeksi sekunder pada penderita HIV dan AIDS. Tuberkulosis adalah penyakit sistem pernafasan kronis dan cenderung menyebabkan melemahnya sistem kekebalan tubuh (immunocompromised). Namun sampai saat ini cryptosporidiosis paru sebagai infeksi sekunder di penderita tuberkulosis belum pernah dilaporkan. Tujuan penelitian ini adalah untuk menentukan jumlah penderita penyakit cryptosporidiosis paru di penderita tuberkulosis. Penelitian dilakukan secara kajian potong silang dengan memanfaatkan sampel dahak sisa periksaan penderita tuberkulosis. Temuan ookista Cryptosporidium dalam sampel dahak dilakukan dengan pengecatan modifikasi Ziehl Neelsen. Tiga dari 44 sampel dahak yang diperiksa (6,8%) menunjukkan positif ookista Cryptosporidium. Penemuan ini harus diwaspadai bahwa kemungkinan penularan cryptosporidiosis melalui jalan pernapasan. Meskipun jumlah penderita penyakit cryptosporidiosis paru di antara penderita tuberkulosis rendah, tetapi setiap penderita  tersebut harus dicurigai kemungkinan terjadi infeksi sekunder cryptosporidiosis, sehingga pemeriksaan laboratorik cryptosporidiosis paru perlu disertakan sebagai pemeriksaan rutin pada penderita tuberkulosis.

Keyword :

Pulmonary cryptosporidiosis, secunder infection, sputum sample, tuberculosis patients,


References :

1. Clavel A, Arnal AC, Sanchez EC, Cuesta J, Letona S, Amiguet JA et al ,(1996) Respiratory Cryptosporidiosis : Case Series and Review of Literature USA : Infection No.5

2. Velez RL, Tarazona R, Camacho AG, Mampaso EG, Guerrero A, Moreira V, Villanueva R,(1995) Intestinal and Extraintestinal Cryptosporidiosis in AIDS Patients USA : Eur J. Clin. Microbiol. Infect. Dis

Markell EK, John DT, Krotoski WA,(1999) Markell and Voges’s Medical Parasitology Philadelphia : W.B Sauders Company

4. Mercado R, Buck GA, Manque PA, Ozaki LS,(2007) Cryptosporodium hominis Infection of the Human Respiratory Tract USA : Emerging Infectious Diseases

Warren CA and Guerrant RL,(2007) Clinical Disease and Pathology, In: Cryptosporidium and Cryptosporidiosis New York : CRC Press





Archive Article

Cover Media Content

Volume : 18 / No. : 3 / Pub. : 2012-01
  1. Prothrombin Time And Activated Partial Thromboplastin Time Test’s Result Using Humaclot Va And Sysmex Ca 500
  2. Association Hla-drb1* And Hla-dqb1* With Serum Igm-rf With Rheumatoid Arthritis
  3. Platelets Of Dengue Hemorrhagic Fever
  4. The Diagnostic Value Of Tb Antigen Using Rapid Test Device (tb Ag) For Pulmonary Tuberculosis
  5. Antimicrobial Susceptibility Test Of Pathogenic Aerobic Bacteria At The Internal Medicine Ward
  6. Correlation Of Liver Functions Test, And The Grade Of Dengue Hemorrhagic Fever In Children
  7. Pulmonary Cryptosporidiosis In Tbc Patients
  8. Mycobacterium Tuberculosis And Pcr
  9. Oral Immunization With 38-kda Adhesin Protein Of Mycobacterium Tuberculosis On Cd8+ T Cells In Lung
  10. Thrombocytes Count In Acute Coronary Syndrome Related To Low Molecular Weight Heparin (lmwh)}
  11. Acute Fatty Liver Of Pregnancy
  12. Cold Agglutinins In A Community Acquired Pneumonia Patient

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