Catalog :




Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 12 / No. 3 / Published : 2006-07

Related with : Scholar   Yahoo!   Bing

Original Article :

Sepsis diagnosis by procalcitonin

Author :

  1. Buchori*1
  2. Prihatini*2
  1. Bagian/Laboratorium Patologi Klinik FK Unair, RSU Dr. Soetomo
  2. Bagian/Laboratorium Patologi Klinik FK Unair, RSU Dr. Soetomo

Abstract :

Sepsis can be difficult to distinguish from non-infections conditions in critically ill patients with clinical signs of inflammation. Diagnosis of sepsis by conventional methods (erythrocyte sedimentation rate, CRP) are difficult to be confirmed. Procalcitonin (PCT) was found in 1990s, which number was enhanced in bacterial and fungi infections. Procalcitonin (PCT) is calcitonin (PCT) prohormon which presence increasing in sepsis and severe diseases. Procalcitonin (PCT) can be measured in serum and plasma by immunolometric methods (immunoassay). The process needs 30 minutes to 1.5 hours depends on the selected method. It can be hope in the future, that methods of Procalcitonin (PCT) measurement can used as a means for early sepsis detection and can distinguish between systemic infection and acute inflammatory disease.

Keyword :

procalcitonin, sepsis, inflammation,


References :

  1. , (2006). Infection control: Basic concepts and practices, 2nd Ed, http://www.heific.org/oldsite/Manual/toc.htm, (accessed Mei,2006).. - : -
  2. O’Connor EO, (2001). Procalcitonin in Critical Illness. Crit Care Res. - : -
  3. Assicot, (1993). High serum procalcitonin concentrations in patients
    with sepsis and infection. Lancet. - : -
  4. Gendrel, (1993). High serum procalcitonin concentrations in patients
    with sepsis and infection. Lancet. - : -
  5. Carsin, (1993). High serum procalcitonin concentrations in patients
    with sepsis and infection. Lancet. - : -
  6. Raymond, (1993). High serum procalcitonin concentrations in patients
    with sepsis and infection. Lancet. - : -
  7. Guilbaud, (1993). High serum procalcitonin concentrations in patients
    with sepsis and infection. Lancet. - : -
  8. Bohuon, (1993). High serum procalcitonin concentrations in patients
    with sepsis and infection. Lancet. - : -
  9. Bohuon, (1993). High serum procalcitonin concentrations in patients
    with sepsis and infection. Lancet. - : -
  10. Whicher, (2001). Procalcitonin as an acute phase markers. Ann Clin Biochem. - : -
  11. Bienvenu, (2001). Procalcitonin as an acute phase markers. Ann Clin Biochem. - : -
  12. Monneret, (2001). Procalcitonin as an acute phase markers. Ann Clin Biochem. - : -
  13. Meisner, (1999). Comparison of PCT and CRP Plasma Concentrations at different SOFA scores during the course of Sepsis and MODS. Critical Care. - : -
  14. Tschaikowsky, (1999). Comparison of PCT and CRP Plasma Concentrations at different SOFA scores during the course of Sepsis and MODS. Critical Care. - : -
  15. Palmaers, (1999). Comparison of PCT and CRP Plasma Concentrations at different SOFA scores during the course of Sepsis and MODS. Critical Care. - : -
  16. Hatherill, (1999). Diagnostic markers of infection: comparison of procalcitonin with C reactive protein and leucocyte count. Arch Dis Child. - : -
  17. Tibby, (1999). Diagnostic markers of infection: comparison of procalcitonin with C reactive protein and leucocyte count. Arch Dis Child. - : -
  18. Sykes, (1999). Diagnostic markers of infection: comparison of procalcitonin with C reactive protein and leucocyte count. Arch Dis Child. - : -
  19. Turner, (1999). Diagnostic markers of infection: comparison of procalcitonin with C reactive protein and leucocyte count. Arch Dis Child. - : -
  20. Murdoch, (1999). Diagnostic markers of infection: comparison of procalcitonin with C reactive protein and leucocyte count. Arch Dis Child. - : -
  21. Chan, (2004). Procalcitonin as a marker of bacterial infection in the emergency departement: an Observational Study. Critical Care. - : -
  22. Tseng, (2004). Procalcitonin as a marker of bacterial infection in the emergency departement: an Observational Study. Critical Care. - : -
  23. Tsay, (2004). Procalcitonin as a marker of bacterial infection in the emergency departement: an Observational Study. Critical Care. - : -
  24. McPhee, (2003). Pathofisiology of Disease An Introduction to Clinical Medicine, 4th Ed.. New York : Lange Medical Books Mc Graw-Hill
  25. Lingappa, (2003). Pathofisiology of Disease An Introduction to Clinical Medicine, 4th Ed.. New York : Lange Medical Books Mc Graw-Hill
  26. Ganong, (2003). Pathofisiology of Disease An Introduction to Clinical Medicine, 4th Ed.. New York : Lange Medical Books Mc Graw-Hill
  27. Shafig, (2005). Estimating the diagnostic accuracy of procalcitonin as a
    petanda of the severity of acute pancreatitis : A Meta Analytic Approach. J Pancreas. - : -
  28. Malhotra, (2005). Estimating the diagnostic accuracy of procalcitonin as a
    petanda of the severity of acute pancreatitis : A Meta Analytic Approach. J Pancreas. - : -
  29. Bhasin, (2005). Estimating the diagnostic accuracy of procalcitonin as a
    petanda of the severity of acute pancreatitis : A Meta Analytic Approach. J Pancreas. - : -
  30. Rana, (2005). Estimating the diagnostic accuracy of procalcitonin as a
    petanda of the severity of acute pancreatitis : A Meta Analytic Approach. J Pancreas. - : -
  31. Siddhu, (2005). Estimating the diagnostic accuracy of procalcitonin as a
    petanda of the severity of acute pancreatitis : A Meta Analytic Approach. J Pancreas. - : -
  32. Pandhi, (2005). Estimating the diagnostic accuracy of procalcitonin as a
    petanda of the severity of acute pancreatitis : A Meta Analytic Approach. J Pancreas. - : -
  33. Whang, (1998). Serum calcitonin precursor in sepsis and systemic inflammation. J Clin Endocrinol Metab. - : -
  34. Steinwald, (1998). Serum calcitonin precursor in sepsis and systemic inflammation. J Clin Endocrinol Metab. - : -
  35. White, (1998). Serum calcitonin precursor in sepsis and systemic inflammation. J Clin Endocrinol Metab. - : -
  36. Nylen, (1998). Serum calcitonin precursor in sepsis and systemic inflammation. J Clin Endocrinol Metab. - : -
  37. Snider, (1998). Serum calcitonin precursor in sepsis and systemic inflammation. J Clin Endocrinol Metab. - : -
  38. Simon, (1998). Serum calcitonin precursor in sepsis and systemic inflammation. J Clin Endocrinol Metab. - : -
  39. Goldberg, (1998). Serum calcitonin precursor in sepsis and systemic inflammation. J Clin Endocrinol Metab. - : -
  40. Becker, (1998). Serum calcitonin precursor in sepsis and systemic inflammation. J Clin Endocrinol Metab. - : -


   


Archive Article

Cover Media Content

Volume : 12 / No. : 3 / Pub. : 2006-07
  1. Sepsis diagnosis by procalcitonin
  2. The haematology reference value of healthy adult people based on sysmex xt-1800i
  3. Bacteria pattern and antibiotic susceptibility test of pregnant women with asymptomatic bacteriuria)
  4. Bacterial pattern and it’s sensitivity in patients suffering from urinary tract infection
  5. Diagnostic test of plasmodium malaria by immunochromatographic method compared to microscopic examination
  6. Troponin t value/ctnt of patients with acute coronary syndrome)
  7. Plasma cell leukemia
  8. The implementation of concept mapping for quality management in a clinical laboratory
  9. The analysis of urethral stone profile at the clinical pathology laboratory