UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 13 / No. 2 / Published : 2007-03

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Original Article :

The diagnostic value of a cassette immunochromatographic test as a diagnostic and in dhf adult patients

Author :

  1. Kusuma Pindayani*1
  2. Aryati -*2
  3. Y. Probohoesodo*3
  1. Bagian Patologi Klinik FK Unair/RSU Dr. Soetomo Surabaya
  2. Bagian Patologi Klinik FK Unair/RSU Dr. Soetomo Surabaya
  3. Bagian Patologi Klinik FK Unair/RSU Dr. Soetomo Surabaya

Abstract :

A rapid immunochromatographic test that incorporates blue particle conjugated with recombinant dengue envelope protein, antihuman IgM monoclonal antibodies and antihuman IgG monoclonal antibodies (Virotec Dengue IgG/IgM XP; Indec Diagnostics, Indonesia using technology of USA) was evaluated by using IgG and IgM captured ELISA (Dengue Duo ELISA, Panbio) which has a 99% sensitivity and a 92% specificity as the “gold standard”. This assay, cassette in shape, is performed in 15–30 minutes and detects both immunoglobulin M (IgM) and IgG in a capture format. There were 57 paired sera of dengue haemmorhagic fever (according to WHO 1997 criterias) and 72 sera of non dengue haemmorhagic fever patients (typhoid fever, UTI, malaria, chikungunya, hepatitis and pneumonia). For the diagnosis of dengue virus infection, the rapid test showed a sensitivity of 98%, positive predictive value of 88%, negative predictive value of 98% and specificity of 99%. The rapid test is a useful aid in rapid diagnosis and differentiation between primary and secondary dengue virus infection.

Keyword :

immunochromatographic cassette, dengue haemmorhagic fever,


References :

Soegijanto S, Sustini F, Wirahjanto A,(2004) Epidemiologi Demam Berdarah Dengue Surabaya : Airlangga University Press





Archive Article

Cover Media Content

Volume : 13 / No. : 2 / Pub. : 2007-03
  1. Features Of Igm – Igg Rapid Serological Test And Routine Hematology Analysis Of Dhf Patients
  2. Profile Of Cholesterol And Albumin Concentration And Urine Sediment Based On Nephrotic Syndrome Children
  3. Analysis Of Serum Albumin Level With Ratio De Ritis In Hepatitis B Patients
  4. Congenital Rubella Syndrome Based On Serologic And Rna Virus Examination
  5. Adult Acute Lymphoblastic Leukemia With Bilineage Phenotipic (b And T-lymphoid)
  6. The Diagnostic Value Of A Cassette Immunochromatographic Test As A Diagnostic And In Dhf Adult Patients
  7. Strategic Prioritization In Clinical Laboratory Services Using Sfas Technique By Means Of Swot Matrix
  8. Creatinine And Creatinine Clearance Value Of Leptospirosis Patients

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