Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN 0854-4263
Vol. 16 / No. 1 / Published : 2009-11
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Original Article :
The evaluation of transaminase activities, and bilirubin level in patients with hepatitis b virus and c virus
Author :
- Yosepin*1
- Benny Rusli*2
- Hardjoeno*3
- Departemen Patologi Klinik, Fakultas Kedokteran Universitas Hasanuddin, RS Dr. Wahidin Sudirohusodo, Makassar
- Departemen Patologi Kinik FK - UNHAS - RS. Dr. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan Km 10 Talamarea Makassar
- Departemen Patologi Kinik FK - UNHAS - RS. Dr. Wahidin Sudirohusodo Jl. Perintis Kemerdekaan Km 10 Talamarea Makassar
Abstract :
Hepatitis virus replicates only in hepatocyte. In hepatocyte injury, transaminase enzymes which normally intracellularly will transform to the blood circulation. And there are variation of increasing transaminase activities in HBV and HCV. To evaluate transaminase activities, and bilirubin level in patients with HBV and HCV. Study design was cross sectional of 76 patients with HBV and HCV, data from medical record at Wahidin Sudirohusodo Hospital, Makassar, from January 2006 until July 2008 period. Data was analyzed with Mann Whitney test using SPSS. windows versi on 12. of 76 patients with HBV and HCV were found 59 Men and 17 women, age 15–72 years old. In there were no statistical significance between transaminase activites, bilirubin direct,indirect (p > 0.05), but there was significance difference of total bilirubin between HBV and HCV (p < 0.05). There were no statistical difference of AST, ALT, bilirubin direct and bilirubin indirect between HBV and HCV. Injury hepatocelluler because of HBV and HCV can not be identified just by transaminase activities and bilirubin level, but there are other factor that influence.
Keyword :
HBV, HCV, transaminase, bilirubin,
References :
Bahrun U, Hardjoeno,(2007) Kapita Selekta Hepatitis Virus Interprestasi Hasil Laboratorium Makassar : Cahya Dinan Rucitra
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