Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN 0854-4263
Vol. 14 / No. 3 / Published : 2008-07
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Original Article :
The immunosupression of renal transplantation) (part ii
Author :
- Suprapto Ma’at*1
- Divisi Penyakit Infeksi Departemen Patologi Klinik Fak. Kedokteran Universitas Airlangga
Abstract :
Renal transplantation is the treatment of choice for most patients with end stage renal disease. Most of the time, transplantation rejection is immunological mediated. Both T cells and circulating antibodies are induced against allograft. Successful organ transplantation requires the use of immunosuppressive drugs to prevent the host’s immune system from rejecting the transplanted organ. The development of immunosuppressive drugs is the key to successful allograft function Immunosuppressive agents are used for induction (intense immunosuppressant in the initial days after transplantation), maintenance and reversal of established rejection. This review focuses on agents that are either approved or in phase 2 or phase 3 trials in kidney transplantation.
Keyword :
Immunosupression, renal transplantation,
References :
Halloran PF,(2004) Immunosuppressive drugs for kidney transplantation London : The new englang journal of medicine
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Volume : 14 / No. : 3 / Pub. : 2008-07 |
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