Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN 0854-4263
Vol. 13 / No. 1 / Published : 2006-11
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Original Article :
The value of sdldl of youngsters and its correlation with other lipids
Author :
- Nurahmi*1
- S.Aprianti*2
- Hardjoeno*3
- Bagian Patologi Klinik FK-UNHAS - BLU RS. Wahidin Sudirohusodo
Makassar. Jl.Perintis Kemerdekaan Km 10. Makassar - Bagian Patologi Klinik FK-UNHAS - BLU RS. Wahidin Sudirohusodo
Makassar. Jl.Perintis Kemerdekaan Km 10. Makassar - Bagian Patologi Klinik FK-UNHAS - BLU RS. Wahidin Sudirohusodo
Makassar. Jl.Perintis Kemerdekaan Km 10. Makassar
Abstract :
In Indonesia, coronary heart disease (CHD) as the cause of death is still the highest in number. It is estimated that the number of deaths is about 535 per 100.000 population. Atherosclerosis represents the main risk factor which could be predicted through the presence of small dense LDL (sdLDL) in youngsters. To determine the value of sdLDL in youngsters and its correlation with other lipids, a study was conducted cross sectionally in Makassar, from January to August 2006, on 125 youngsters aged 15 to 19 years. Their total cholesterol, HDL, LDL, TG and ApoB was determined and sdLDL was derived from calculation of LDL/apoB ≤ 1.2. 69 (55.20%) patients showed sdLDL value and 56 (44.8%) patients did not show sdLDL value. Statistical calculation showed a significant correlation between sdLDL and HDL level (p = 0.001), sdLDL and TG level (p = 0.003), and sdLDL and ApoB level (p = 0.036). Percentage of sdLDL value was higher in youngsters aged 15 to 19. This proves that the process of atherosclerosis happened early at a young age. Showed by the existence of sdLDL and therefore sdLDL could be used as a predictor of atherosclerosis which can be prevented if detected earlier.
Keyword :
small dense LDL, atherosclerosis, Coronary Heart Disease,
References :
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Hardjoeno,(2006)
Archive Article
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