UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Clinical Pathology and Medical Laboratory

ISSN 0854-4263

Vol. 16 / No. 2 / Published : 2010-03

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Original Article :

Various bacterial cultures related to their susceptibility against several types of antibiotics

Author :

  1. Carolina M Viany S*1
  2. Aryati*2
  1. Bagian Patologi Klinik, Fakultas Kedokteran Universitas Airlangga – RSUD Dr. Soetomo Surabaya
  2. Departemen Patologi Klinik FK Universitas Airlangga – RSUD Dr. Soetomo Jl. Prof. Mayjen Moestopo 6-8 Surabaya

Abstract :

Infection is the major public health problem in Indonesia which could increase its morbidity and mortality. The antibiotics treatment which were given irrationally leads to bacteria susceptibility and worsen the problem. One of the efforts to manage the bacteria susceptibility the physician has to know the bacterial pattern and its characteristic to resist various antibiotics. The information may contribute as a reference to give antibiotic therapy in a rational manner. To know the bacterial susceptibility pattern against various antibiotics a study was carried out using specimens derived from several hospitals which referred them to a private laboratory in Surabaya. The specimens consisted of blood, urine and sputum were referred during September 2007 up to July 2008. The identification of the bacteria and it‘s susceptibility pattern were carried out by a conventional method and an auto analyzer (Vitek 2 Compact). The antibiotic susceptibility test was carried out by conventional method using Kirby Bauer modifiied diffusion technique and Vitec 2 Compact using MIC reference. The results showed that the most common bacteria found from blood was Escherichia coli which was still sensitive to amoxicillin-clavulanic acid, amikacin, and cefepim. And from the urine was Escherichia coli which were still sensitive to meropenem followed by amikacin and gentamycin. Whereas from the sputum was found Streptococcus α haemolyticus which was still sensitive to amoxicillin-clavulanic acid, piperacillin tazobactam, linezolid. The result of the antibiotic susceptibility test is mostly dominated by the Betalactam group, such as amoxicillin-clavulanic acid and carbapenem group like meropenem. Besides of that, in this study was also found multiple drug resistance organisms (MDRO), such as Escherichia coli ESBL, Enterobacter liquefaciens ESBL, Enterobacter agglomerans ESBL, Klebsiella ozaenae ESBL, and Klebsiella pneumoniae ESBL. The susceptibility pattern of the bacteria derived from blood and sputum is dominated by gram positive cocci. Whereas from urine is dominated by Gram negative rods.

Keyword :

Various bacterial cultures, Susceptibility, Antibiotics,


References :

M.G,(1996) Cftazidime-resistant klebsiella pneumoniae and escherichia coli bloodstream infection Washington DC : J Infect Dis





Archive Article

Cover Media Content

Volume : 16 / No. : 2 / Pub. : 2010-03
  1. Serum Albumin Level In Ischemic And Hemorrhagic Stroke Patients
  2. Microbial Resistance And Sensitivity Pattern To Antimicrobial Drug
  3. Various Bacterial Cultures Related To Their Susceptibility Against Several Types Of Antibiotics
  4. Analysis Of Eosininophil On Acute Interstitial Nephritis
  5. Von Willebrand Kinetic Factor In Adult Dengue Haemorrhagic Fever Patients
  6. Immature To Total Neutrophil (i/t) Ratio As Septic Neonatorum Diagnostic
  7. Hdl Cholesterol Concentration Measured Using Cholestest N Hdl And Hdl-c Plus 3rd Generation Reagents
  8. Molecul Detection Of Rpob Gene Mutation In Mycobacterium Tuberculosis With Polymerase Chain Reaction And Singgle Strand Conformation Polymorphism
  9. The Diagnosis Molecular And Aplication In Treatment Of B & C Hepatitis
  10. Swine Influenza A/h1n1 Confirmed By Pcr
  11. Sd Dengue Duo (ns1, Igg, Igm) Rapid Test For The Diagnosis Of Dengue Virus Infection
  12. The Management Of An Emergency Laboratory

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