UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 46 / No. 3 / Published : 2013-09

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Original Article :

Correlation between salivary leptin levels and incidence of caries in obese children

Author :

  1. Elfrida Atzmaryanni*1
  2. Mochamad Fahlevi Rizal*2
  1. Departemen Ilmu Kedokteran Gigi Anak Fakultas Kedokteran Gigi, Universitas Indonesia, Jakarta – Indonesia
  2. Departemen Ilmu Kedokteran Gigi Anak Fakultas Kedokteran Gigi, Universitas Indonesia, Jakarta – Indonesia

Abstract :

Background: Children with obesity have a lower incidence of caries. Salivary leptin levels of obese children is higher than normal children. Leptin is protein hormone, contained in saliva. Salivary proteins is to maintain the balance of the ecosystem in the mouth.Purpose: To find the correlation beetween salivary leptin levels with caries experience in normal and obese children. Review: Mouth is reflection of the health status and so many changes occur as a weight gain. Child with obesity has a low incidence of caries than normal. This condition is associated with changes in oral cavity, especially the increase in salivary leptin. Caries is a disease of hard tissues cause by the activty of microorganisms, especially Streptococcus mutans. Salivary proteins is to maintain the balance of the ecosystem in the mouth. Leptin is a protein saliva, produced predominantly in adipose tissue and conduct active transport to saliva. Salivary leptin works in two ways: as an antimicrobial which prevents the attachment of bacteria on tooth surface or by inducing cytokine that affect the immune system in oral cavity. Conclusion: Salivary leptin is higher in obesity. The low incidence of caries on obesity is associated with salivary leptin. Alteration in salivary composition and flow rate also decreased caries in obesity.

Keyword :

Obesity, salivary leptin , dental caries,


References :

Karthikeyan BV,(2007) Leptin levels in gingival crevicular fluid in periodontal health and disease - : J Periodont Res





Archive Article

Cover Media Content

Volume : 46 / No. : 3 / Pub. : 2013-09
  1. Correlation Between Salivary Leptin Levels And Incidence Of Caries In Obese Children
  2. The Role Of Calcium On Enamel Hypoplasia Prevention
  3. The Correlation Of Micronucleus Formation And 8-oxo-dg Expression Due To The Panoramic Radiography Exposure
  4. Fluoride Determination Of Children And Adult Toothpaste By Spectrophotometry
  5. Heteroplasmy Analysis Of Dental Pulp Mitochondrial Dna In Forensic Personal Identification
  6. Effect Of Gestational Diabetes Mellitus On The Expression Of Amelogenin In Rat Offspring Tooth Germ
  7. The Effect Of Chitosan Gel Concentration To Neutrophyl And Macrophage In Gingival Ulcer
  8. Epstein-barr Virus (ebv) Dna As Biomaker Of Nasopharyngeal Carcinoma Diagnosis
  9. Metal Crown Restoration With Fiber Post In Young First Permanent Molar
  10. Cranial Size And Cephalic On Index Mentally Retarded 7–12 Years Old Children
  11. Mechanism Of Pomegranate Extract In Killing Malignant Cells In Mice Through Oral Cavity Mucosa Increased Expression Of P53 Wild

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