UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 41 / No. 3 / Published : 2008-07

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Original Article :

Cytotoxicity of 5% tamarindus indica extract and 3% hydrogen peroxide as root canal irrigation

Author :

  1. Erawati*1
  1. Department of Conservative Dentistry
    Faculty of Dentistry Jember University
    Jember - Indonesia

Abstract :

Background: Preparation of root canal is an important stage in endodontic treatment. During conducting preparation, it is always be followed with root canal irrigation that has aim to clean root canal from necrotic tissue remains, grind down dentin powder, micro organism, wet the root canal to make preparation process of root canal easier, and solute root canal content at area that can not be reached by equipment. Flesh of Tamarindus indica (pulpa tamarindorum) is used as traditional medicine and it contains vitamin C (antioxidant), protein, fat, glucose, etc. Previous research shows that 5% tamarindus indica extract can clean smear layer but it is more cytotoxicity to cell line BHK–21 than sterilized aquabides. Purpose: This research is to compare cytotoxicity between 5% indica extract with 3% H2O2 as root canal irrigation material. Method: Four teen culture cell line BHK 21 divides into 2 groups. 1 is treated with 3% H2O2 and Group 2 is treated with 5% Tamarindus indica extract, for about 2.5 minutes in every group. Then, living and death cell percentage is measured. Data is analyzed with independent t test with significant level of 0.05%. Result: The research showed that death cell in group 1 was 29.3% and in group 2 was 21.1%. There was a significant different (p < 0.05) between group 1 and group 2. Conclusion: Cytotoxicity of 5% Tamarindus indica extract to the cell line BHK–21 is lower than 3% H2O2.

Keyword :

cytotoxicity, Tamarindus indica extract, hydrogen peroxide, root canal irrigation,


References :





Archive Article

Cover Media Content

Volume : 41 / No. : 3 / Pub. : 2009-09
  1. Cytotoxicity Test Of 40, 50 And 60% Citric Acid As Dentin Conditioner By Using Mtt Assay On Culture Cell Line
  2. Cytotoxicity Of 5% Tamarindus Indica Extract And 3% Hydrogen Peroxide As Root Canal Irrigation
  3. The Effectiveness Of 0.5–0.7% Tetracycline Gel To Reduced Subgingival Plaque Bacteria
  4. The Profile Of Upper Integument Lip Of Baduy And The Nearby Living Sundanese In South Banten, West Java, Indonesia
  5. Isolation And Identification Of Java Race Amniotic Membrane Secretory Leukocyte Protease Inhibitor Gene
  6. The Role Of Proper Treatment Of Maxillary Sinusitis In The Healing Of Persistent Oroantral Fistula
  7. The Management Of Oral Candidosis In Diabetic Patient With Maxillary Herpes Zoster
  8. Non-invasive Endodontic Treatment Of Large Periapical Lesions
  9. Potential Role Of Odontoblasts In The Innate Immune Response Of The Dental Pulp
  10. The Use Of Bay Leaf (eugenia Polyantha Wight) In Dentistry
  11. Effect Of Various Temperature And Storage Duration On Setting Time Of Orega Sealer

Information DENTJ