Dental Journal (Majalah Kedokteran Gigi)
ISSN 1978-3728
Vol. 42 / No. 4 / Published : 2009-10
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Original Article :
Detection of aggressive periodontitis by calprotectin expression
Author :
- Desi Sandra Sari*1
- Suryono*2
- Department of Periodontics
Faculty of Dentistry,University of Jember - Department of Periodontics
Faculty of Dentistry, University of Gadjah Mada
Abstract :
Background: Calprotectin is a calcium--binding protein expressed by neutrophil, monocytes, gingival keratinocytes, and oral epithelial cells. The concentrations of calprotectin increase in plasma, urine and synovial fluid of patients with inflammatory diseases. This protein is known as a marker for periodontal diseases and is detected in gingival crevicular fluids. Purpose: This study was aimed to investigate the detection of inflammation on the aggressive periodontitis by calprotectin expression. Methods: The gingival crevicular fluids were taken from five aggressive periodontitis patients and five healthy subjects by using sterile paper points. Calprotectin expression was analyzed by ELISA technique. Rresult: The results showed the significant difference in calprotectin expression between subject with aggressive periodontitis and healthy subjects p = 0.002 (p < 0.05). Conclusion: It was concluded that the calprotectin expression on the aggressive periodontitis patients may be useful for evaluation the progression of inflammation in periodontitis.
Keyword :
Calprotectin, aggressive periodontitis, gingival crevicular fluids,
References :
Archive Article
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Volume : 42 / No. : 4 / Pub. : 2009-12 |
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