UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 41 / No. 2 / Published : 2008-04

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Original Article :

Differences in cytotoxicity between 5% tetracycline hydrochloride and 15% edta as root canal irrigant

Author :

  1. Devi Eka Juniarti*1
  2. Karlina Samadi*2
  3. Achmad Sudirman*3
  1. Department of Conservative Dentistry
    Faculty of Dentistry Airlangga University
    Surabaya - Indonesia
  2. Department of Conservative Dentistry
    Faculty of Dentistry Airlangga University
    Surabaya - Indonesia
  3. Department of Conservative Dentistry
    Faculty of Dentistry Airlangga University
    Surabaya - Indonesia

Abstract :

Tetracycline hydrochloride 5% and EDTA 15% as a root canal irrigant have been proven to be able remove smear layer, open dentinal tubules and have antimicrobial activity. An effective root canal irrigation solution must be able to dissolve organic and anorganic debris, lubricated endodontic instruments, disinfect microorganism and non toxic. The purpose of this laboratory experimental study was to determine cytotoxicity differences between tetracycline hydrochloride 5% and EDTA 15%. 21 samples were used and classified into 3 groups: control, tetracycline hydrochloride 5% and EDTA 15% groups. Cytotoxicity test was done using BHK21 cells. The data was analyzed using Bird and Forrester formula. It concluded that tetracycline hydrochloride 5% more toxic than EDTA 15% as a root canal irrigant.

Keyword :

cytotoxicity, tetracycline hydrochloride 5% , EDTA 15% , cell fibroblast,


References :





Archive Article

Cover Media Content

Volume : 41 / No. : 2 / Pub. : 2008-06
  1. The Role Of Partial Denture In Management Of Hypohidrotic Ectodermal Dysplasia
  2. Management Of Zygomatic-maxillary Fracture (the Principles Of Diagnosis And Surgical Treatment With A Case Illustration)
  3. The Transversal Strength Of Acrylic Resin Plate After Soaking In The Juice Of The Noni Fruit (morinda Citrifolia Linn.)
  4. Pulp Tissue Inflammation And Angiogenesis After Pulp Capping With Transforming Growth Factor β1
  5. The Effect Of Exposure Duration Of Self Etch Dentin Bonding On The Toxicity Of Human Gingival Fibroblast Of Cell Culture
  6. Effect Of Il-1 And Gustducin Expression Change On Bitter Taste During Fever
  7. Differences In Cytotoxicity Between 5% Tetracycline Hydrochloride And 15% Edta As Root Canal Irrigant
  8. The Level Of Streptococcus Mutans And Lactobacillus In Saliva Of Dental Caries And Free Caries Children
  9. Combination Of Natural Teeth And Osseointegrated Implants As Prosthesis Abutments In A Posterior Cantilever Bridge
  10. Students’ Evaluation Of Preclinical Simulation For All Ceramic Preparation (in Faculty Of Dentistry Universiti Kebangsaan Malaysia)
  11. Potency Of Probiotic Therapy For Dental Caries Prevention
  12. The Use Of 90% Aloe Vera Freeze Drying As The Modulator Of Collagen Density In Extraction Socket Of Incicivus Cavia Cobaya

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