UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 44 / No. 2 / Published : 2011-09

Order : 11, and page :111 - 116

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Original Article :

Effect of soybean extract after tooth extraction on osteoblast numbers

Author :

  1. Rosa Sharon Suhono*1
  2. Coen Pramono Danudiningrat*2
  3. Djodi Asmara*3
  1. Student Faculty of Dentistry, Airlangga University Surabaya - Indonesia
  2. Department of Oral and Maxillofacial Surgery Faculty of Dentistry, Airlangga University Surabaya - Indonesia
  3. Department of Oral and Maxillofacial Surgery Faculty of Dentistry, Airlangga University Surabaya - Indonesia

Abstract :

Background: Many researches were done to find natural materials that may increase and promote bone healing processes after trauma and surgery. One of natural material that had been studied was soybean extract which contains phytoestrogen, a non-steroidal compounds found in plants that may binds to estrogen receptors and have estrogen-like activity. Purpose: The aim of this study was to investigate the effect of soybean extract feeding on the number of osteoblast cells in alveolar bone socket after mandibular tooth extraction. Methods: This study was studied on male Rattus norvegicus strain Wistar. Seventeen rats divided into three groups were used in this study. Group 1 fed with carboxy methyl cellulose (CMC) solution 0,2% for seven days, and the left mandibular central incisivus was extracted; group 2 fed with soybean extract for seven days and the left mandibular central incisives was extracted; group 3 received the left mandibular central incisives extraction followed by soybean extract feeding for seven days after the extraction. All groups were sacrificed on the seventh day post-extraction, and the alveolar bone sockets were taken for histopathological observation. The tissues were processed and stained using hematoxylin and eosin to identify the amount of osteoblast cells. The number of osteoblast cells was counted using an Image Tool program. The data was analyzed statistically using the One-Way ANOVA test. Results: Significant differences were found on the number of osteoblast cells in alveolar bone after tooth extraction between groups. Group 2 (fed with soybean extract) is higher than group 1 (fed with CMC) and group 3 (fed with soybean extract after extraction). Conclusion: Soybean extract feeding that given for seven days pre-tooth extraction can increase the number of osteoblast cells compared with the group that were not given soybean extract feeding and also with the group that were given soybean extract feeding for seven dayspost-tooth extraction. 

Keyword :

Tooth extraction, soybean extract, phytoestrogen, osteoblast,


References :

Peterson LJ,(2003) Contemporary oral and maxilofacial surgery. Jakarta : EGC





Archive Article

Cover Media Content

Volume : 44 / No. : 2 / Pub. : 2011-06
  1. The Effectivity Of Toothpick Tooth Brushing Method On Plaque Control
  2. Effects Of Different Saliva Ph On Hybrid Composite Resin Surface Roughness
  3. Endothelial Cell Cultured On Ha/tcp/chitosan Scaffold For Bone Tissue Engineering
  4. Elderly Nutritional Status Affect Salivary Anticandidal Capacity Against Candida Albicans
  5. Saliva As A Future Potential Predictor For Various Periodontal Diseases
  6. Relieving Idiopathic Dental Pain Without Drugs
  7. Effectivity Of 0.15% Benzydamine On Radiation-induced Oral Mucositis In Nasopharynx Carcinoma
  8. Constraints On The Performance Of School-based Dental Program In Yogyakarta Province, Indonesia: (a Qualitative Study)
  9. Orthodontic Treatment With Skeletal Anchorage System
  10. The Activity Of Stichopus Hermanii Extract On Triglyceride Serum Level In Periodontitis
  11. Effect Of Soybean Extract After Tooth Extraction On Osteoblast Numbers

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