UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 44 / No. 3 / Published : 2011-09

Order : 6, and page :141 - 144

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Original Article :

Efficacy of various topical agents to prevent enamel demineralization

Author :

  1. Priska Lestari Hendrawan*1
  2. Erwin Siregar*2
  3. Krisnawati*3
  1. Orthodontic Resident Faculty of Dentistry, University of Indonesia Jakarta - Indonesia
  2. Department of Orthodontics Faculty of Dentistry, University of Indonesia Jakarta - Indonesia
  3. Department of Orthodontics Faculty of Dentistry, University of Indonesia Jakarta - Indonesia

Abstract :

Background: Enamel demineralization is a common and undesirable side effect of fixed appliance orthodontic treatment. Many sudies showed that the prevalence varied between 2–96%. There are many ways to prevent demineralization and increased remineralization such as oral hygiene instruction and by topical application such as acidulated phosphate fluor (APF) casein phospo peptide-amorphous calcium phosphate (CPP-ACP), casein phospo peptide-amorphous calcium phosphate plus (CPP-ACPF). Purpose: The purpose of this in-vitro study was to evaluate the efficacy of various topical agents to prevent enamel demineralization. Methods: Fourty extracted human premolars were allocated to 1 of 4 groups: 1.23% APF gel; 10% CPP-ACP paste; 10% CPP-ACPF paste; and untreated control. All samples were subjected to pH cycling treatment for 12 days through a daily procedure of demineralization solution with pH 4 for 6 hours and remineralization solution with pH 7 for 18 hours. Microhardness testing were done before and after pH cycling and the delta hardness values were determined. Results: APF, CPP-ACP and CPP-ACPF application significantly prevent lowering of enamel microhardness value compared with untreated control group. Kruskal-Wallis, ANOVA, Mann-Whitney U, Tukey and Bonferroni Post-Hoc multiple comparison test showed significant difference between mean delta microhardness value of CPP-ACPF and CPP-ACP group with APF group, but there is no significant difference between mean delta microhardness value of CPP-ACPF and CPP-ACP group. Conclusion: APF, CPP-ACP and CPP-ACPF prevent enamel demineralization. CPP-ACP and CPP-ACPF prevent demineralization more than APF.

Keyword :

Enamel demineralzation, topical agents, enamel microhardness testing,


References :

Gorelick L,(2004) Incidence of white spot formation after bonding and banding - : Am J Orthod





Archive Article

Cover Media Content

Volume : 44 / No. : 3 / Pub. : 2011-09
  1. The Role Of Probiotic On Alveolar Bone Resorption
  2. Dental Measurements Of Deuteromalayid Javanese Students Of The Faculty Of Dentistry Airlangga University
  3. Recent Pharmacological Management Of Oral Bleeding In Hemophilic Patient
  4. Treatment Of Lingual Traumatic Ulcer Accompanied With Fungal Infections
  5. The Effectiveness Of Nigella Sativa Seed Extract In Inhibiting Candida Albicans On Heat Cured Acrylic Resin
  6. Efficacy Of Various Topical Agents To Prevent Enamel Demineralization
  7. Threshold Value Of Enamel Mineral Solubility And Dental Erosion After Consuming Acidic Soft Drinks
  8. Anterior Makeover On Fractured Teeth By Simple Composite Resin Restoration
  9. Management Of Horizontal Crown Fracture Caused By Traumatic Injury With Endorestoration Treatment
  10. Sensitivity Difference Of Streptococcus Viridans On 35% Piper Betle Linn Extract And 10% Povidone Iodine Towards Recurrent Apthous Stomatitis
  11. Odontoblast Layer Structure Alteration As A Response To Carious Lesions

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