UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 43 / No. 2 / Published : 2010-06

Order : 1, and page :49 - 53

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Original Article :

Erythema multiforme as the result of taking carbamazepine

Author :

  1. Maharani Laillyza Apriasari*1
  2. M. Jusri*2
  1. Resident of Oral Medicine
  2. Department of Oral Medicine

Abstract :

Background: Erythema multiforme is an acute mucocutaneus disease which is caused by the hypersensitivity reaction. It is characterized by target lesions on the skin or ulcerative oral lesion. Etiology of the disease is unknown, it is currently considered as immunologic disease. The triggering factors are because of the use of certain type of drugs like antibiotics, anticonvulsant, and NSAID. Most of the dentists do not know about it’s mechanism, so a lot of people consider it as a malpractice. Purpose: This paper reported a case of a man, 46 years old which had ulcerative oral mucous, peeled and pain lips after taking carbamazepine drugs. Case: The clinical diagnosis of this case was erythema multiforme because of the hypersensitivity reaction as the result of taking carbamazepine drugs. Case management: The final diagnosis based on anamnesis history of taking systemic drugs and clinical manifestation of erythema multiforme in the oral cavity. The drugs therapy that had been given were antihistamine, oral corticosteroid, gargle liquid contained of topical anesthetic, corticosteroid, and antibiotic. Conclusion: In this case, it can be concluded that erythema multiforme appeared was triggered by taking carbamazepine as drugs of choice for Trigeminal Neuralgia therapy. These drugs can cause type III hypersensitivity reaction. The final diagnosis based on anamnesis history of the use carbamazepine drugs before lesions erupted and the characterized clinical manifestation.   

Keyword :

erythema multiforme, carbamazepine, hypersensitivity,


References :

George L,(2005) Treatment of oral disease: A concise textbook Stuttgart : Thieme





Archive Article

Cover Media Content

Volume : 43 / No. : 2 / Pub. : 2010-06
  1. Intregrated Orofacial Therapy In Chronic Rhinosinusitis Management For Children With Sleep Bruxism
  2. Erythema Multiforme As The Result Of Taking Carbamazepine
  3. Tensile Bond Strength Of Hydroxyethyl Methacrylate Dentin Bonding Agent On Dentin Surface At Various Drying Techniques
  4. The Efficacy Of Honey Solution As Plaque Reducing Agent
  5. Optimum Dose Of 2-hydroxyethyl Methacrylate Based Bonding Material On Pulp Cells Toxicity
  6. Ankylosis Of The Temporomandibular Joint And Mandibular Growth Disturbance Caused By Neglected Condylar Fracture In Chilhood
  7. The Effect Of Monofluorophosphate Implant In White Rat Mothers Towards The Level Of Fluor In The Incisors Of The Young Babies (rattus-rattus)
  8. Early Removal Of  Odontoma Resulting In Spontaneous Eruption Of  The Impacted  Teeth
  9. Dental Modificantions: A Prespective Of Indonesia Chronology And The Current Applications
  10. Enamel Defect Of Deciduous Teeth In Small For Gestational Age Children
  11. Integrated Orofacial Therapy In Chronic Rhinosinusitis Management For Children With Sleep Bruxism
  12. The Apical Leakage Of Mineral Trioxide Agregate As The Retrograde Filling Material With Various Mixing Agents  

Information DENTJ