UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 47 / No. 1 / Published : 2014-03

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Original Article :

Induction of spirulina chitosan gel into cavia cobaya socket toward healing process post extraction

Author :

  1. Rostiny*1
  2. Mefina Kuntjoro*2
  3. Ratri Maya Sitalaksmi*3
  4. Sherman Salim*4
  1. Dosen Fakultas Kedokteran Gigi
  2. Dosen Fakultas Kedokteran Gigi
  3. Dosen Fakultas Kedokteran Gigi
  4. Dosen Fakultas Kedokteran Gigi

Abstract :

Background:  Prominent residual ridge is necessary to gain retention and stabilility for succesful prosthodontic treatment such as removable, fixed or implant . Meanwhile tooth extraction procedure can damage periodontal tissue, cementum and alveolar bone that cause greater residual ridge resorbtion. Spirulina is a natural substance that can help tissue healing and chitosan also a natural substance that was proven have the ability to help bone remodelling. This combination gel can become an alternative material to maintain residual ridge height after tooth extraction. Purpose: To prove this combination gel effective to prevent greater residual ridge resorbtion by counting the amount of osteoclast, osteoblast and kolagen as an indicator for healing process. Methods: This research was done by using 28 cavia cobaya divided into 4 groups, control group, group 1, 2, and 3.  Insisive mandible extraction was done and the sockets were filled with CMCNa 3% for control groups,  spirulina 3% chitosan 200 mg for group 1, spirulina 6 % chitosan 200 mg for group 2, spirulina 12% chitosan 200 mg for group 3. After 30 days, histopathology examination was done by using microscope to count the amount of osteoclas, osteoblas and collagen. Results:  Data was analyzed by using Anova and Tukey HSD. For osteoclast, there was no significant different between every groups.  While for osteoblast and collagen there was significant different between group. Conclusion: Combination gel spirulina 12% chitosan 200 mg can be alternative material for better bone remodeling after tooth extraction.  

Keyword :

Spirulina, chitosan, bone remodeling, tissue healing,


References :

Topazian RG,(2002) Oral and maxillofacial infections USA : Elsevier Saunders





Archive Article

Cover Media Content

Volume : 47 / No. : 1 / Pub. : 2014-03
  1. Combination Of Aloe Vera And Xenograft Induction On Decreasing Of Nf-kb Of Tooth Extraction Socket Preservation In Cavia Cobaya
  2. Role Of Hsp60, Cd-8 And Ifn-γ On The Imunopatobiogenesis Of Periapical Granuloma On Dental Caries
  3. The Expressions Of Nf-κβ And Tgfβ-1 On Odontoblast-like Cells Of Human Dental Pulp Injected With Propolis Extracts
  4. Induction Of Spirulina Chitosan Gel Into Cavia Cobaya Socket Toward Healing Process Post Extraction
  5. Alkaline Phosphatase Expression During Relapse After Orthodontic Tooth Movement
  6. Antimicrobial Proteins Of Snail Mucus (achatina Fulica) Against Streptococcus Mutans And Aggregatibacter Actinomycetemcomitans
  7. The Effect Of Immersion In Soda On Nano Hybrid Composite Resin Discoloration
  8. The Role Of Heat Shock Protein 27 (hsp 27) As Inhibitor Apoptosis In Hypoxic Conditions Of Bone Marrow Stem Cell Culture
  9. The Sensitivity And Specificity Test Of Pediatric Caries Predictor Software
  10. The Effect Of Position And Volumetric Fraction Polyethylene Fiber On The Flexural Strength Of Fiber Reinforced Composite
  11. Oral Hygiene And Number Of Oral Mucosal Lesion Correlate With Oral Health-related Quality Of Life In Elderly Communities Of Yogyakarta City

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