UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 45 / No. 2 / Published : 2012-06

Order : 5, and page :84 - 88

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Original Article :

Inhibition of 10% alpinia galanga and alpinia purpurata rhizome extract on candida albicans growth

Author :

  1. Fakhrurrazi*1
  2. Rachmi Fanani Hakim*2
  3. Cut Cahya*3
  1. Dentistry Study Program, Faculty of Medicine, Syiah Kuala University Aceh - Indonesia
  2. Dentistry Study Program, Faculty of Medicine, Syiah Kuala University Aceh - Indonesia
  3. Dentistry Study Program, Faculty of Medicine, Syiah Kuala University Aceh - Indonesia

Abstract :

Background: One of normal oral flora that found in human oral cavity is Candida albicans (C. albicans). The overgrowth of this species can lead to opportunistic infection known as candidiasis. Two natural plants, Alpinia galanga rhizome and Alpinia purpurata rhizome, are natural remedies containing flavonoid, saponin, tannin, and triterpenoid used as antifungal component. Purpose: This experimental laboratory study, is aimed to determine the inhibition of Alpinia galanga rhizome and Apinia purpurata rhizome on the growth of C. albicans. Methods: Alpinia galanga rhizome and Alpinia purpurata rhizome were extracted in ethanol solvent using soxhletation method. The ratio test was conducted on those two extracts at the concentration of 10% toward the growth of C. albicans through agar diffusion method. Results: The results showed that 10% Alpinia galanga rhizome extract and 10% Alpinia purpurata rhizome extract were able to inhibit the growth of C. albicans, about 7.33 mm for Alpinia galanga rhizome extract and 6 mm for Alpinia purpurata rhizome extract. The results of statistical tests using independent samples t-test showed that there was no significant difference between the inhibition of 10% Alpinia galanga rhizome extract and that of 10% Alpinia purpurata rhizome extract. Conclusion: In conclusion 10% Alpinia galanga rhizome extract and 10% Alpinia purpurata rhizome extract have weak inhibition on C. albicans growth.

Keyword :

Candida albicans, candidiasis, Alpinia galanga rhizome, Alpinia purpurata rhizome,


References :

Samaranayake LP,(2002) Essential microbiology for dentistry London, UK : Churchill, Livingstone, Elsevier





Archive Article

Cover Media Content

Volume : 45 / No. : 2 / Pub. : 2012-06
  1. The Importance Of Masticatory Functional Analysis In The Diagnostic Finding And Treatment Planning For Prosthodontic Rehabilitation
  2. The Management Of Chronic Traumatic Ulcer In Oral Cavity
  3. Simplified Digital Infra Red Photography: An Alternative Tool In Bitemark Forensic Investigation
  4. The Relation Between Salivary Siga Level And Caries Incidence In Down Syndrome Children
  5. Inhibition Of 10% Alpinia Galanga And Alpinia Purpurata Rhizome Extract On Candida Albicans Growth
  6. Pulpal Inflammation After Vital Tooth Bleaching With 38% Hydrogen Peroxide
  7. The Increasing Of Enamel Calcium Level After Casein Phosphopeptide-amorphous Calcium Phosphate Covering
  8. Cytotoxicity Of Betel Leaf (piper Betel L.) Against Primary Culture Of Chicken Embryo Fibroblast And Its Effects On The Production Of Proinflammatory Cytokines By Human Peripheral Blood Mononuclear Cells
  9. Deoxypyridinoline Level In Gingival Crevicular Fluid As Alveolar Bone Loss Biomarker In Periodontal Disease
  10. Craniofacial Morphology Of Children With Complete Unilateral Cleft Lip And Palate Following Labioplasty And Palatoplasty
  11. Seroprevalence Of Herpes Simplex Virus Types 1 And 2 And Their Association With Cd4 Count Among Hiv-positive Patients

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