UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 45 / No. 3 / Published : 2012-09

Order : 4, and page :138 - 143

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Original Article :

Medication intake and its influence on salivary profile of geriatric outpatients in cipto mangunkusumo hospita

Author :

  1. Yuniardini Septorini Wimardhani,*1
  2. Winanda Annisa *2
  3. Febrina Rahmayanti*3
  1. Department of Oral Medicine Faculty of Dentistry, Universitas Indonesia, Jakarta - Indonesia
  2. Department of Oral Medicine Faculty of Dentistry, Universitas Indonesia, Jakarta - Indonesia
  3. Department of Oral Medicine Faculty of Dentistry, Universitas Indonesia, Jakarta - Indonesia

Abstract :

Background: It has been well documented that several diseases or conditions and their related medications could be the risk      factors for several ailments found in the oral cavity. Increased usage of medication in elderly could have impact on quality of saliva      that affects oral health, eventually cause deterioration in quality of life. Purpose: To describe the salivary pH, buffering capacity,      stimulated- and unstimulated salivary flow rate profile in elderly using medications. Methods: Seventy-six elderly were consented and      agreed to participate in this study. Interview and medical record analysis were performed to get data about their health status, chronic      use of medications and complaints related to xerostomia. Collection of unstimulated and stimulated saliva samples were completed      in parallel with measurement of salivary pH and buffering capacity. Results: The mean salivary pH was moderately acidic while      having low salivary buffering capacity. The mean unstimulated salivary flow rate (USSFR) was 0.24 ± 1.8ml/min and 41of subjects      (53%) were classified hyposalivation, while the stimulated salivary flow rate (SSFR) was 0.86 ± 0.49ml/min and 31 (40%) classified      hyposalivation. Number of drugs-induced xerostomia intake significantly correlated with the reduction in the USSFR of subjects      (p<0.0001), however it was not the case with salivary pH and buffering capacity (p>0.05). It also showed correlation with complaints      related to xerostomia. The mean USSFR did not correlate with xerostomia complaints. Conclusion: Medications intake influenced      salivary profile and had more effect in changes in xerostomia complaints and salivary quantity than to salivary pH and buffering      capacity in Indonesian elderly population.      

Keyword :

Medication, xerostomia, hyposalivation, elderly,


References :

Petersen PE,(2005) Improving the oral health of older people: the approach of the WHO Global Oral Health Programme - : Community Dent Oral Epidemiol





Archive Article

Cover Media Content

Volume : 45 / No. : 3 / Pub. : 2012-09
  1. The Benefit Of Differential Moment Concept In Managing Posterior Anchorage And Avoiding Bite Deepening
  2. Henoch-schönlein Purpura In Children: Its Relation To Oral And Dental Health
  3. Distribution Of Class Ii Major Histocompatibility Complex Antigen-expressing Cells In Human Dental Pulp With Carious Lesions
  4. Medication Intake And Its Influence On Salivary Profile Of Geriatric Outpatients In Cipto Mangunkusumo Hospita
  5. Maternal Endotoxin-induced Fetal Growth Restriction In Rats: Fetal Responses In Toll-like Receptor
  6. Novel Development Of Carbonate Apatite-chitosan Scaffolds Based On Lyophilization Technique For Bone Tissue Engineering
  7. Analgesic Effect Of Coconut Shell (cocos Nucifera L) Liquid Smoke On Mice
  8. Penetration Effect Of Prostaglandin E2 Gel On Oral Mucosa Of Rats
  9. Shear Bond Strength Of Self-adhering Flowable Composite On Dentin Surface As A Result Of Scrubbing Pressure And Duration
  10. Facial Reconstruction Using Polypropylene Mesh After Resection Of Maxillary Ossifying Fibroma
  11. Physical Characteristic Of Brown Algae (phaeophyta) From Madura Strait As Irreversible Hydrocolloid Impression Material

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