Dental Journal (Majalah Kedokteran Gigi)
ISSN 1978-3728
Vol. 43 / No. 1 / Published : 2010-03
Order : 7, and page :31 - 34
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Original Article :
Mengkudu (morinda citrifolia linn.) gel effect on post-extraction fibroblast acceleration
Author :
- Christian Khoswanto*1
- Department of Oral Biology
Faculty of Dentistry Airlangga University
Surabaya
Abstract :
Background: Tooth extraction is one of treatment frequently which is done by dentists in clinics, hospital, and even private practices. One thing that is needed to be observed after the treatment is the speed of wound recovery process. Mengkudu is commonly used as medicinal treatments, some of them to heal wounds, but there had never been research of the use of mengkudu fruit in wound recovery after tooth extraction. Purpose: The aim of this study was to investigate the effect of mengkudu gel in accelerating the escalation of fibroblast amount post tooth extraction on Dawley rats. Methods: This study was used post test only control group design. Thirty male Dawley rats weigh between 250-300 grams, 3 months of age are being used. Tooth extraction is being done on lower left incisor. The 30 rats are divided into three groups. The data were analyzed statistically using One-Way ANOVA and LSD0.05. Result: The result of every tested group showed p>0.05, therefore all the data had a normal distribution. Therefore, a One-Way ANOVA test with 5% significant rate was done and continued by LSD test to find a significant difference in each groups. Examination showed there was significant difference in fibroblast amount between the group with mengkudu gel and two other groups (p<0.05). Conclusion: The application of mengkudu gel can accelerate the escalation of fibroblast amount after the tooth extraction on Dawley rats.
Keyword :
Fibroblast, mengkudu, extraction ,
References :
Saptyono B. ,(1996) Pengaruh aplikasi lokal getah pisang pada penyembuhan luka pasca pencabutan gigi cavis cobaya - : Majalah Kedokteran Gigi
Archive Article
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Volume : 43 / No. : 1 / Pub. : 2010-03 |
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