UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 40 / No. 1 / Published : 2007-01

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Original Article :

Molecular study of the dentin-pulp complex responses to caries progression

Author :

  1. Yani Corvianindya Rahayu*1
  1. Department of Oral Biology, University of Jember Faculty of Dentistry Jember - Indonesia

Abstract :

The dentin-pulp complex exhibits various responses to caries, including events of injury, defense, and repair. The overall responses dependent on pulp cell activity and the signaling processes, which regulate the behavior of these cells. The signals for tissue repair are thought to be mediated by dentin-bound growth factors released during caries progression. Growth factors are a key of molecules responsible for signaling a variety of cellular process following dental injury. The endogenous proteolytic enzymes (Matrix metalloproteinases, MMPs) present in dentin matrix might also participate in releasing bioactive molecule. Several members of the MMP family are found in the soft and hard tissue compartment of dentin-pulp complex. Their presumed role in many physiological process during the development and maintenance of the dentin-pulp complex, they may also contribute to the pathogenesis of dentin caries and the responses elicited by caries.

Keyword :

dentin-pulp complex, molecular events, caries progression ,


References :





Archive Article

Cover Media Content

Volume : 40 / No. : 1 / Pub. : 2007-03
  1. Effect Of Combination Antiretroviral Therapy On The Frequency Of Oral Candidiasis In Hiv/aids Patient
  2. Oral And Dental Management In Children With Tetralogy Of Fallot
  3. Understanding About The Classification Of Pulp Inflammation
  4. Electro-gene Therapy In A Human Oral Tongue Cancer Cell By Intratumoral Injection Of Pcdna3._-p27kip_ Wt
  5. Molecular Study Of The Dentin-pulp Complex Responses To Caries Progression
  6. A Comparison Of Three Dimensional Changein Maxillary Complete Dentures Between Conventional Heatpolymerizing And Microwave Polymerizing Techniques
  7. U Bow Activator, An Alternative Functional Orthodontic Appliance
  8. Closure Of Oroantral Fistula With Rotational Palatal Flap Technique
  9. Chronic Periodontitis As An Etiology Of Sleep Disturbances And Premenstrual Syndrome (pms)
  10. The Effect Of Hegu Acupoint Stimulation In Dental Acupuncture Analgesia
  11. Placement Of Fin Type Dental Implant In Three Different Surgical Situations Of Alveolar Bone

Information DENTJ