UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 43 / No. 2 / Published : 2010-06

Order : 4, and page :62 - 66

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Original Article :

Optimum dose of 2-hydroxyethyl methacrylate based bonding material on pulp cells toxicity

Author :

  1. Widya Saraswati*1
  1. Department of Conservative Dentistry Faculty of Dentistry, Airlangga University Surabaya - Indonesia

Abstract :

Background: HEMA (2-hydroxyethyl methacrylate), one type of resins commonly used as bonding base material, is commonly used due to its advantageous chemical characteristics. Several preliminary studies indicated that resin is a material capable to induce damage in dentin-pulp complex. It is necessary to perform further investigation related with its biological safety for hard and soft tissues in oral cavity. Purpose: The author performed an in vitro test (on fibroblast culture of dental pulp) in this study to find optimum dose of HEMA resin monomer that may induce toxicity in pulp fibroblast cells. Method: The method of this study was experimental laboratory with post test control group design. Primary cell culture was made from dental pulp fibroblast cells, and was given with HEMA resin bonding material in various concentrations (5 µg/ml–2560 µg/ml), and then subjected to toxicity test (MTT assay). Result: HEMA optimum concentration was 320 µg/ml to induce cytotoxicity in pulp fibroblast cells. Conclusion: HEMA-based bonding material may induce pulp fibroblast cells toxicity.

Keyword :

Citotoxicity, HEMA, resin, bonding material, fibroblast cells,


References :

Soeprapto M. ,(1999) Kultur jaringan (hewan) (tissue culture) Surabaya : Program Pascasarjana Universitas Airlangga





Archive Article

Cover Media Content

Volume : 43 / No. : 2 / Pub. : 2010-06
  1. Intregrated Orofacial Therapy In Chronic Rhinosinusitis Management For Children With Sleep Bruxism
  2. Erythema Multiforme As The Result Of Taking Carbamazepine
  3. Tensile Bond Strength Of Hydroxyethyl Methacrylate Dentin Bonding Agent On Dentin Surface At Various Drying Techniques
  4. The Efficacy Of Honey Solution As Plaque Reducing Agent
  5. Optimum Dose Of 2-hydroxyethyl Methacrylate Based Bonding Material On Pulp Cells Toxicity
  6. Ankylosis Of The Temporomandibular Joint And Mandibular Growth Disturbance Caused By Neglected Condylar Fracture In Chilhood
  7. The Effect Of Monofluorophosphate Implant In White Rat Mothers Towards The Level Of Fluor In The Incisors Of The Young Babies (rattus-rattus)
  8. Early Removal Of  Odontoma Resulting In Spontaneous Eruption Of  The Impacted  Teeth
  9. Dental Modificantions: A Prespective Of Indonesia Chronology And The Current Applications
  10. Enamel Defect Of Deciduous Teeth In Small For Gestational Age Children
  11. Integrated Orofacial Therapy In Chronic Rhinosinusitis Management For Children With Sleep Bruxism
  12. The Apical Leakage Of Mineral Trioxide Agregate As The Retrograde Filling Material With Various Mixing Agents  

Information DENTJ