UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 46 / No. 4 / Published : 2013-12

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Original Article :

Prevotella intermedia and porphyromonas gingivalis in dental caries with periapical granuloma

Author :

  1. Risya Cilmiaty*1
  2. Afiono Agung Prasetyo*2
  1. Department of Dental and Oral Disease, Faculty of Medicine, Universitas Sebelas Maret, Surakarta-Indonesia
  2. 2Department of Microbiology, Faculty of Medicine Universitas Sebelas Maret, Surakarta- Indonesia 3A-IGIC Research Group, Universitas Sebelas Maret, Surakarta-Indonesia 4Center of Biotechnology and Biodiversity Research and Development, Universitas Sebelas Maret, Surakarta-Indonesia

Abstract :

Background: Dental caries with necrotic pulp is an infectious multifactorial disease that attacks enamel until pulp chamber of the tooth. The anaerobic bacteria infection in the pulp chamber could induce the formation of periapical granuloma. However, the presence of the most frequently anaerobic bacteria identified in apical periodontitis, Porphyromonas gingivalis and Prevotella intermedia, in Indonesian periapical granuloma have not been confirmed. Purpose: To confirm the presence of the black pigmented anaerobic bacteria, Porphyromonas gingivalis and Prevotella intermedia, in Indonesian dental caries with necrotic pulp and evaluate its relation with periapical granuloma. Methods: Thirty-six patients of dental caries with necrotic pulp in General Hospital Dr. Moewardi in Surakarta, Indonesia were involved and classified into two groups, with and without periapical granuloma. The tooth caries was extracted, and the chronic periapical tissue was then swabbed and cultured on blood agar medium in anaerobic condition. The bacterial DNA was extracted from the positive cultures and subjected for molecular assays. Results: Periapical granuloma was more likely found in women (OR 5.5, 95% CI=1.277-23.693; RR 2.5, 95% CI= 1.025-6.100). Black colonies bacteria were associated with periapical granuloma (OR 2.2, 95% CI=0.517-9.594; RR 1.5, 95% CI=0.655-3.623). Porphyromonas gingivalis and Prevotella intermedia were detected in dental caries tissues, with or without periapical granuloma, however, only Prevotella intermedia was associated with periapical granuloma (OR 1.6, 95% CI=0.418-5.903; RR 1.3, 95% CI=0.653-2.393). Conclusion: The presence of Porphyromonas gingivalis and Prevotella intermedia in Indonesian periapical granuloma were confirmed, however, only Prevotella intermedia were associated with periapical granuloma.

Keyword :

Dental caries, necrotic pulp, periapical granuloma, Prevotella intermedia, Porphyromonas gingivalis,


References :

Deljo E,(2013) Prevalence of dental caries in the municipality gorazde during the period 2007-2012 - : Mater Sociomed





Archive Article

Cover Media Content

Volume : 46 / No. : 4 / Pub. : 2013-12
  1. Prevotella Intermedia And Porphyromonas Gingivalis In Dental Caries With Periapical Granuloma
  2. Facial Soft Tissue Profile On Borderline Class I Malocclusion Between Extraction And Non-extraction Orthodontic Treatment
  3. Ekspresi Cox-2 Setelah Pemberian Ekstrak Etanolik Kulit Manggis
  4. Fish Oil Of Sardinella Longicep Regulates Osteoblast Apoptosis Of Rat Alveolar Bone Induced Lypopolisacharide
  5. Inflammatory Response Of The Dental Pulp After Application Of 19% Ethylene Diamine Tetraacetic Acid And 37% Phosphoric Acid As Etching Agents
  6. Potential Of Extracts Cassava Leaf (manihot Utilissima) On The Expression Of Cox-2 On Monocytes That Exposed By Lps E. Coli
  7. The Effect Of Desensitizing Agent Containing Fluoride On Streptococcus Mutans Adhesion And Enamel Roughness
  8. Physical Properties Of Calcite Synthesized Hydroxyapatite As The Filler Of Epoxy-resin-based Root Canal Sealer
  9. Antifungal Property Of Sticophus Hermanii And Holothuria Atra Extract And Its Cytotoxicityto Gingiva-derived Mesenchymal Stem Cell
  10. Orthodontic-surgical Treatment Of A Severe Class Iii Malocclusion
  11. Perbandingan Korelasi Antara Indeks Morfologi Wajah Genap Dengan Sudut Interinsisal Dan Tinggi Wajah Secara Sefalometri

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