UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 41 / No. 1 / Published : 2008-01

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Original Article :

Pulp tissue vacuolization and necrosis after direct pulp capping with calcium hydroxide and transforming growth factor-1

Author :

  1. Sri Kunarti*1
  1. Department of Conservative Dentistry
    Faculty of Dentistry Airlangga University
    Surabaya - Indonesia

Abstract :

Mechanical pulp exposure by a rotary cutting instrument or a hand-cutting instrument often happens in deep caries. Application of protective dressing can protect the pulp from additional injury by facilitating healing and repair. Pulp capping has been suggested as one treatment of choice after pulp exposure to maintain pulp vitality. TGF-1 is growth factor that has important rule in wound healing. The application of Ca(OH)2 and exogenous TGF-1 as direct pulp capping tr4eatment must be experimented in-vivo to see the vacuolization and necrosis in7,14 and 21 days after application. This research was done in vivo experiment from orthodontic patients indicated for premolar extraction, between ages 10-15 years. A class V cavity preparation was created in the buccal aspect 1 mm above gingival margin until pulp exposure. Cavity was irrigated slowly with saline solution and dried with a sterile small cotton pellet. Group 1 calcium hydroxide was applied as manufacture procedure. Group 2, the sterile absorbable collagen membrane used, as inert carrier of TGF-1 was soaked with 5 l. All groups were covered by a Teflon pledge to separate pulp capping agent from glass ionomer cement restoration. Teeth extracted in 7, 14 and 21 days after treatment. All samples were hystopathologically examined. There were significant difference of TGF-1 (p

Keyword :

direct pulp capping, Ca(OH)2 , TGF-1, vacuolization, necrosis ,


References :

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Burns,(2002) Pathways of the pulp St Louis : Mosby Inc

Craig,(2000) Cement: Dental materials properties and manipulation St Louis : Mosby Inc

Power,(2000) Cement: Dental materials properties and manipulation St Louis : Mosby Inc

Wataha,(2000) Cement: Dental materials properties and manipulation St Louis : Mosby Inc

Hu,(1998) Reparative dentin formation in rat molars after direct pulp capping with growth factors St Louis : Journal Endodontic

Zhang,(1998) Reparative dentin formation in rat molars after direct pulp capping with growth factors St Louis : Journal Endodontic

Qian,(1998) Reparative dentin formation in rat molars after direct pulp capping with growth factors St Louis : Journal Endodontic

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Archive Article

Cover Media Content

Volume : 41 / No. : 1 / Pub. : 2008-03
  1. Three Dimensional Changes In Maxillary Complete Dentures Immersed In Water For Seven Days After Polymerization
  2. The In Vitro Assessment Of Anti Proliferation Activity Of Crude Diethyl Ether Extract Of Dendrophthoe Species To Myeloma Culture Cell
  3. Coen’s Ascending Ramus Fixator Use For Repositioning The Ascending Ramus During Mandible Reconstruction
  4. The Role Of Transforming Growth Factor Beta In Tertiary Dentinogenesis
  5. Morphological Changes Of Alveolar Bone Due To Orthodontic Movement Of Maxillary And Mandibulary Incisors
  6. The Effect Of Psidium Guajava Linn Leaf Extract On Candida Albicans Adherence And The Transversal Strength Of Acrylic Resin
  7. Side Effects Of Mercury In Dental Amalgam
  8. Pulp Tissue Vacuolization And Necrosis After Direct Pulp Capping With Calcium Hydroxide And Transforming Growth Factor-1
  9. Antimicrobial Effect Of Calcium Hydroxide As Endo Intracanal Dressing On Streptococcus Viridans
  10. Gingival Immunologic Defense Index: A New Indicator For Evaluating Dental Plaque Infection Risk In Allergic Children
  11. Expression Toll-like Receptors In The Oral Mucosal Of Patients With Recurrent Aphthous Stomatitis