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Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 44 / No. 3 / Published : 2011-09

TOC : 3, and page :127 - 131

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Original Article :

Recent pharmacological management of oral bleeding in hemophilic patient

Author :

  1. Monica Widyawati Setiawan *1
  1. Faculty of Pharmacy, Widya Mandala University Surabaya - Indonesia

Abstract :

Background: Hemophilia is a hereditary bleeding disorder that can increase the risk of disease in oral cavity. Sometimes hemophilia is not always established already in a patient. The lack of awareness of hemophilia presence can cause serious problem. Purpose: The purpose of this review is to explain about dental bleeding manifestation and management in hemophilic patient. Reviews: Hemophilia can be manifested as dental bleeding that cannot stop spontaneously. It should be treated with factor VIIII either by giving whole blood, fresh plasma, fresh frozen plasma, cryoprecipitate, and factor VIII concentrate. Factor VIII dose for hemophilia treatment can be calculated based on factor VIII present in hemophilia patient’s body. Factor VIII can also be given as prophylaxis to prevent bleeding. Complications that can be caused by factor VIII replacement therapy are the presence of factor VIII inhibitor and transfusion related diseases. Treatment of dental bleeding due to hemophilia consists of factor replacement therapy and supportive therapy. Conclusion: Treatment of dental bleeding due to hemophilia consists of factor replacement therapy and supportive therapy. There are complications that can happen due to factor VIII replacement therapy that should be considered and anticipated.

Keyword :

Hemophilia patient, oral bleeding, management,


References :

  1. Monroe DM, (2010). Molecular biology and biochemistry of the coagulation factors and pathways of hemostatis. . New York : Williams Hematology


   


Archive Article

Cover Media Content

Volume : 44 / No. : 3 / Pub. : 2011-09
  1. The role of probiotic on alveolar bone resorption
  2. Dental measurements of deuteromalayid javanese students of the faculty of dentistry airlangga university
  3. Recent pharmacological management of oral bleeding in hemophilic patient
  4. Treatment of lingual traumatic ulcer accompanied with fungal infections
  5. The effectiveness of nigella sativa seed extract in inhibiting candida albicans on heat cured acrylic resin
  6. Efficacy of various topical agents to prevent enamel demineralization
  7. Threshold value of enamel mineral solubility and dental erosion after consuming acidic soft drinks
  8. Anterior makeover on fractured teeth by simple composite resin restoration
  9. Management of horizontal crown fracture caused by traumatic injury with endorestoration treatment
  10. Sensitivity difference of streptococcus viridans on 35% piper betle linn extract and 10% povidone iodine towards recurrent apthous stomatitis
  11. Odontoblast layer structure alteration as a response to carious lesions