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Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 42 / No. 4 / Published : 2009-10

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Original Article :

The ability of igy to recognize surface proteins of streptococcus mutans by using western blot method

Author :

  1. Basri A. Gani*1
  2. Santi Chismirina*2
  3. Zinatul Hayati*3
  4. Endang Winiati B*4
  5. Boy M Bachtiar*5
  6. I. Wayan T. Wibawan*6
  1. Department of Oral Biology
    Dentistry Faculty, Syiah Kuala University, Banda Aceh
  2. Department of Oral Biology
    Dentistry Faculty, Syiah Kuala University, Banda Aceh
  3. Department of Microbiology, Dentistry Faculty, Syiah Kuala University, Banda Aceh
  4. Department of Oral Biology, Dentistry Faculty, Indonesia University, Jakarta
  5. Department of Oral Biology, Dentistry Faculty, Indonesia University, Jakarta

  6. Department of Bacteriology and Immunology, Vertirinary Faculty, Pertanian Bogor Institute, Bogor

Abstract :

Background: Streptococcus mutans are gram positive bacteria classified into viridians group, and have a role in pathogenesis of dental caries. It’s adhesion to the tooth surface is mediated by cell surface proteins, which interact with specific receptor located in tooth pellicle. Glucan binding protein, Glukosyltransferase, and antigen I/II are basic proteins of S. mutans, which have a role in initiating the interaction. A previous study showed that chicken’s IgY can interfere the interaction. Purpose: The objective of this study is to assess the ability of IgY in recognizing the surface molecule of Streptococcus mutans expressed by various serotypes (c, d, e, f) and a strain derived from IPB, Bogor. Method: Western blot was used as a method to determine such capability. Result: The result showed that IgY has a potency to recognize antigen I/II, but not the other proteins on the cell surface of all bacteria tested. Conclusion: The ability of IgY to bind the surface protein, antigen I/II, indicates that this avian antibody could be used as a candidate for anti-adhesion in preventing dental caries.

Keyword :

IgY, Streptococcus mutans, adhesion, surface proteins, and dental caries ,


References :





Archive Article

Cover Media Content

Volume : 42 / No. : 4 / Pub. : 2009-12
  1. Immunopathological Aspects Of Oral Erythema Multiforme
  2. Cemento-ossifying Fibroma Of The Jaw
  3. Fibrous Epulis Associated With Impacted Lower Right Third Molar
  4. Correction Parameters In Conventional Dental Radiography For Dental Implant
  5. Evaluation Of Seat And Non-seat Post Preparation Design Using Conventional And Computational Methods
  6. Detection Of Aggressive Periodontitis By Calprotectin Expression
  7. The Ability Of Igy To Recognize Surface Proteins Of Streptococcus Mutans By Using Western Blot Method
  8. The Management Of Over Closured Anterior Teeth Due To Attrition
  9. Treatment Results Evaluation Using The Index Of Orthodontic Treatment Need

Information DENTJ