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Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 44 / No. 2 / Published : 2011-06

TOC : 10, and page :106 - 110

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Original Article :

The activity of stichopus hermanii extract on triglyceride serum level in periodontitis

Author :

  1. Rima Parwati Sari *1
  2. Syamsulina Revianti *2
  1. Department of Oral Biology Faculty of Dentistry, University of Hang Tuah Surabaya - Indonesia
  2. Department of Oral Biology Faculty of Dentistry, University of Hang Tuah Surabaya - Indonesia

Abstract :

Background: The level of triglyceride can be used as a parameter of hypercholesterolemia. Periodontitis can make the condition of hypercholesterolemia worse. Stichopus hermanii extract is a source of saturated fatty acid containing omega-3 which can decreasetriglyceride blood level. Purpose: The aim of this research was to investigate the effect of Stichopus hermanii extract in triglyceride blood level of wistar rats which got periodontitis. Methods: The samples of this research were 30 rats divided into 5 groups, namely group K(–) as negative control group (without treatment), group K(+) as positive control group (induced with periodontopathogen mix), group P1 as treatment group1 (induced with periodontopathogen and Stichopus hermanii extract mix, 0.09 ml/kgW), Group P2 (induced with periodontopathogen and Stichopus hermanii extract mix, 0,18 ml/kgW), and group P3 (induced with periodontopathogen and Stichopus hermanii extract mix, 0,36 ml/kgW). Then, all of those rats were sacrificed and all serum was measured for their level of triglyceride. Results: All data was analyzed with ANOVA test showing a significant result. LSD test showed a significant different between group K(–) and group K(+), and between group K(+) and group P2 and P3. Conclusion: Stichopus hermanii extract can decrease the triglyceride blood level in wistar rats with periodontitis.

Keyword :

Hypercholesterolemia, triglyceride, Stichopus hermanii extract, periodontitis, omega-3,


References :

  1. Sari RP, (2009). Black seed (Nigella sativa) effect to the number of lymphocytes and plasma cells in mice (Mus musculus) gingival induced by mix bacteria.. - : Maj Ked Gigi Edisi khusus Timnas


   


Archive Article

Cover Media Content

Volume : 44 / No. : 2 / Pub. : 2011-06
  1. The effectivity of toothpick tooth brushing method on plaque control
  2. Effects of different saliva ph on hybrid composite resin surface roughness
  3. Endothelial cell cultured on ha/tcp/chitosan scaffold for bone tissue engineering
  4. Elderly nutritional status affect salivary anticandidal capacity against candida albicans
  5. Saliva as a future potential predictor for various periodontal diseases
  6. Relieving idiopathic dental pain without drugs
  7. Effectivity of 0.15% benzydamine on radiation-induced oral mucositis in nasopharynx carcinoma
  8. Constraints on the performance of school-based dental program in yogyakarta province, indonesia: (a qualitative study)
  9. Orthodontic treatment with skeletal anchorage system
  10. The activity of stichopus hermanii extract on triglyceride serum level in periodontitis
  11. Effect of soybean extract after tooth extraction on osteoblast numbers