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Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 43 / No. 3 / Published : 2010-09

Order : 8, and page :141 - 145

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Original Article :

The combination of miacalcic, calcium lactate, and vitamin c as post-extraction alveolar bone resorption inhibitor

Author :

  1. Sri Kentjananingsih *1
  1. Department of Biology, Surabaya State University Surabaya - Indonesia

Abstract :

Background: Tooth extraction can cause alveolar resorption, then and the reduction of denture retention. The process of bone resorption looks like in osteoporosis. Calcium and vitamin D supplementation is rational therapy for minimizing bone loss. Miacalcic is the drug of choice for osteporotic patient. Purpose: This study is aimed to know whether the combination of miacalcic, Ca-lactate, vitamin C are effective in inhibiting post extracted alveolar resorption. Methods: Thirty three healthy postmenopausal women were used as samples and they were classified randomly into control group (without treatment), 1st experiment group (treatment was started 3 months post extraction), and 2nd experiment group (treatment was started at the 2nd day post extraction). This research used a completely randomized design. The treatment was giving miacalcic nasal spray, Ca-lactate 500 mg and vitamin C 100 mg tablets every morning in 10 days every month for 3 months. X-ray photo of the post extracted area were taken an hour, 3 months, and 6 months post extraction. Results: After 6th month, there was significant difference about buccolingual thickness decreasing among three groups (p<0.05). The maximum mean difference of buccolingual thickness decreasing was 0.72 mm, between control and 2nd experiment groups. There was non significant difference about bone density decreasing among them (p > 0.10). The maximum difference of the mean of density decreasing was 1,906 g/cm2/mm between control and 2nd experiment groups. The increasing density occurred mostly in the 2nd experiment group. Conclusion: The combination of miacalcic, Ca-lactate, and vitamin C are effective for inhibiting alveolar resorption, although statistically there was no significant difference about bone density decreasing. The sooner this treatment is given the better result will be achieved.

Keyword :

Miacalcic, Ca-lactate, vitamin C, alveolar resorption,


References :

Peterson LJ,(1992) Principles of oral and maxillofacial surgery Philadelphia : JB Lippincott Co





Archive Article

Cover Media Content

Volume : 43 / No. : 3 / Pub. : 2010-09
  1. Computer Aided Diagnosis For Osteoporosis Based On Trabecular Bone Analysis Using Panoramic Radiographs
  2. Anti-inflammation Effects Of Sardinella Longicep Oils Against Paw Oedema On Rattus Novergicus Induced By 1% Carrageenan
  3. The Correlation Between Immunoexpression Of Estrogen Receptor And The Severity Of Periodontal Disease
  4. The Effectiveness Of Sharp End And Rounded End Bristle Toothbrush
  5. Contact Hypersensitivity After Using  Tongue Piercing
  6. Cervical End Preparation Design Of Collarless Metal Ceramic Crown To The Decrease Of Bacterium Colony Number
  7. Treatment Of Sharp Mandibular Processus Alveolaris With Hybrid Prosthesis
  8. The Combination Of Miacalcic, Calcium Lactate, And Vitamin C As Post-extraction Alveolar Bone Resorption Inhibitor
  9. The Molecular Pheomena Of  The Blaz Genes   Forming Beta-lactamase Enzymes Structure In Staphylococcus Aureus Resistant To Beta-lactam Antibiotics (ampicillin)
  10. Management Of Idiopathic Alveolar Bone Necrosis Associated With Oroantral Fistula After Upper Left  First Molar Extraction
  11. Indirect Veneer Treatment Of Anterior Maxillary Teeth With Enamel Hypoplasia

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