UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 43 / No. 3 / Published : 2010-09

Order : 3, and page :117 - 121

Related with : Scholar   Yahoo!   Bing

Original Article :

The correlation between immunoexpression of estrogen receptor and the severity of periodontal disease

Author :

  1. Yuliana Mahdiyah Da’at Arina*1
  2. S. Sunardhi Widyaputra*2
  3. Koeswadji*3
  1. Departement of Periodontology, Faculty of Dentistry, Jember University, Jember-Indonesia
  2. Departement of Oral Biology, Faculty of Destistry and Departement of Pathology Anatomi, Faculty of Medicine Padjadjaran University, Bandung-Indonesia
  3. Department of Biochemistry, Faculty of Medicine, Padjadjaran University, Bandung-Indonesia

Abstract :

Background: The decrease of estrogen in menopause period may be one of the risk factors of periodontal disease. The influence of estrogen to periodontal tissue disturbance is mediated by the presence of estrogen receptor on tissue. The precise mechanism how the estrogens mediate this effect is still unclear. Purpose: The aim of this study is to determine the correlation between estrogen receptor a and b on the periodontal pocket of women who had severe chronic periodontitis measured based on the periodontal pocket depth. Methods: Twenty four periodontitis patients from menopausal and productive women according to the criteria were examined upon her periodontal status and immunoexpression of estrogen receptor a and b on their periodontal pocket wall. Results: The result showed that in the menopausal and productive women, immunoexpression of estrogen receptor a and b is not correlated with the periodontal pocket depth (p>0.05). However, the pocket depth seemed to show higher correlation with immunoexpression of estrogen receptor a than that with estrogen receptor b, r=0.37 vs. r=0.12 for menopausal women, and r=41 vs. r=0.11 for productive women. Conclusion: It was concluded that no significant correlation was found between the estrogen receptor and periodontal pocket depth both on menopausal and productive women, presumed that estrogen has little role in the severity of periodontitis based on periodontal pocket depth. However, the estrogen receptor a has valuable effect on the severity of periodontal disease more than the estrogen receptor ß.

Keyword :

Estrogen, estrogen receptor α and ß, periodontal disease/ severity, periodontal pocket ,


References :

Mascarenhas P,(2003) Influence of sex hormones on the periodontium - : J Clin Periodontol





Archive Article

Cover Media Content

Volume : 43 / No. : 3 / Pub. : 2010-09
  1. Computer Aided Diagnosis For Osteoporosis Based On Trabecular Bone Analysis Using Panoramic Radiographs
  2. Anti-inflammation Effects Of Sardinella Longicep Oils Against Paw Oedema On Rattus Novergicus Induced By 1% Carrageenan
  3. The Correlation Between Immunoexpression Of Estrogen Receptor And The Severity Of Periodontal Disease
  4. The Effectiveness Of Sharp End And Rounded End Bristle Toothbrush
  5. Contact Hypersensitivity After Using  Tongue Piercing
  6. Cervical End Preparation Design Of Collarless Metal Ceramic Crown To The Decrease Of Bacterium Colony Number
  7. Treatment Of Sharp Mandibular Processus Alveolaris With Hybrid Prosthesis
  8. The Combination Of Miacalcic, Calcium Lactate, And Vitamin C As Post-extraction Alveolar Bone Resorption Inhibitor
  9. The Molecular Pheomena Of  The Blaz Genes   Forming Beta-lactamase Enzymes Structure In Staphylococcus Aureus Resistant To Beta-lactam Antibiotics (ampicillin)
  10. Management Of Idiopathic Alveolar Bone Necrosis Associated With Oroantral Fistula After Upper Left  First Molar Extraction
  11. Indirect Veneer Treatment Of Anterior Maxillary Teeth With Enamel Hypoplasia

Information DENTJ