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Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 39 / No. 2 / Published : 2006-04

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Original Article :

The density of collagen fiber in alveolus mandibular bone of rabbit after augmentation with powder demineralized bone matrix post incisivus extraction

Author :

  1. Regina*1
  2. Abdul Salam M Sofro*2
  3. Al Supartinah Santoso*3
  4. Marsetyawan HNE Soesatyo*4
  5. Widya Asmara*5
  1. Faculty of Dentistry, Gadjah Mada University, Yogyakarta
  2. Faculty of Medicine, YARSI University, Jakarta
  3. Faculty of Dentistry, Gadjah Mada University, Yogyakarta
  4. Faculty of Medicine, Gadjah Mada University, Yogyakarta
  5. Faculty of Veterinary Medicine, Gadjah Mada University, Yogyakarta

Abstract :

The bone defect due to tooth extraction contributes the most cases reported in the aspects of oral surgery. The defect can be preventively managed by adding powder bone matrix intended for augmentation which eventually induces the formation of new bones. This hard tissue wound healing is preceded by the presence of collagen fibers. The aim of this study was to determine the density of collagen fiber in the alveolus mandibular bone of rabbit which was augmented using powder demineralized bone matrix (DBM) post incisivus extraction. Twenty four male rabbits aged 2.5–3 months weighed 900–1,100 grams were randomly divided into two groups. The treated rabbits were augmented with DBM after the incisivus extraction on mandible. The mucosa was then sutured. On the other hand, the controlled rabbits received similar treatments with those of the treated rabbits except there was no augmentation of DBM. Decapitation of treated and controlled rabbits was made on day 5, 7, 10, and 14 days post surgery, each with three rabbits. Mandibles were cut, decalcified, and imbedded in paraffin block. The staining was done using Mallory. Significant differences in the density of collagen were noted on day 10 and 14 post surgery, indicating that powder demineralized bone matrix successfully induced the stimulation of collagen.

Keyword :

demineralized bone matrix, augmentation, collagen ,


References :

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Kent,(1997) Endosseus implants for maxillofacial reconstruction Philadelphia, London, Toronto, Montreal, Sidney, Tokyo : WB Saunders Co

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Stringer,(1994) Demineralized cortical bone powder: Use in grafting space occupaying lesions of bone - : International Orthopedi

Urist,(1965) Bone: Formation by autoinduction - : Science

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Urist,(1965) Osteogenesis in the anterior of intramuscular implants of decalcified bone matrix - : Clinical Orthopaedic and Rel



Archive Article

Cover Media Content

Volume : 39 / No. : 2 / Pub. : 2006-06
  1. The Density Of Collagen Fiber In Alveolus Mandibular Bone Of Rabbit After Augmentation With Powder Demineralized Bone Matrix Post Incisivus Extraction
  2. Placement Of Replace Select Ti-unite-coated Type Implants Using A Combination Of Immediate And Submerge Techniques After Tooth Extraction
  3. Nursing Habits And Early Childhood Caries In Children Attending Hospital University Science Malaysia (husm)
  4. Tensile Bond Strength Of Hydroxyethyl Methacrylate (hema) Bonding Agent To Bovine Dentine Surface At Various Humidity
  5. Sensitization Of The Sphenopalatine Ganglion (spg) By Periodontal Inflammation: A Possible Etiology Of Sinusitis And Headache In Children
  6. Oral And Dental Aspects Of Child Abuse
  7. The Business Of Dental Practice
  8. The Change Of Temperature On The Shear Strength Of Permanent Soft-liner On Acrylic Resin
  9. Candidosis On Oral Lichen Planus
  10. Surface Hardness Of Hybrid Ionomer Cement After Immersion In Antiseptic Solution

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