UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 40 / No. 3 / Published : 2007-07

Related with : Scholar   Yahoo!   Bing

Original Article :

The determination of phenazone in blood plasma for obtained sistem suitable test of monitoring drug level

Author :

  1. Mochamad Lazuardi*1
  1. Veterinary Pharmacy Subdivision, Veterinary Basic Science
    Veterinary Faculty, Airlangga University
    Surabaya – Indonesia

Abstract :

The determining of Phenazone to human blood plasma from healthy man after separated by solid phase extraction (SPE) and spectroscopic measurements has been investigated. The objective of that research was to obtain system suitable test for determine the Phenazone level in biological fluids (human blood plasma), for new performed dosage regimented in clinical dentistry. The method can be divided into the following four steps. 1. Centrifugation the blood sample, 2. Extraction from blood plasma and, 3. Separation by SPE with manual pressured, 4. Elution to SPE followed by the measurement on a spectrophotometer in the ultra violet region. The critical value of t at the 5% confidence level indicates that there is no systematic error in the linearity proposed method. Recoveries for this research were obtained at ranging 93.460 to 95.598%. The coefficient variation precision of this procedure was clearly good at smallest than 2%. The analytical procedure can be carried out in one working operation as a monitored therapeutic activity.

Keyword :

phenazone, solid phase extraction, spectrophotometer UV-Vis,


References :





Archive Article

Cover Media Content

Volume : 40 / No. : 3 / Pub. : 2007-09
  1. Sealing Ability Of Hydroxyapatite As A Root Canal Sealer: In Vitro Study
  2. Jaw Locking After Maxillofacial Trauma
  3. New Insight In Pediatric Dentistry: Preventive Dentistry In Allergy Management Protocol
  4. The Pattern Of P53 Gene Mutations On Oral Squamous Cell Carcinoma
  5. The Difference Of Tensile Bond Strength Between Total Etch And Self Etch Dentin Bonding On Dentin Surface
  6. The Microbiological Detection Of Mycobacterium Tuberculosis From Oral Lesion
  7. Antibacterial Force Of The Luting-type Of Glass Ionomer Cement Toward Lactobacillus Species And Streptococcus Mutans
  8. Prevalence Of Xerostomia On Type 2 Diabetes Mellitus In Hajj Surabaya
  9. Accuracy Of A Fourth Generation Apex Locator-an In Vitro Evaluation
  10. The Effect Of Acidulated Phosphate Fluoride Application On Dental Enamel Surfaces Hardness
  11. The Determination Of Phenazone In Blood Plasma For Obtained Sistem Suitable Test Of Monitoring Drug Level

Information DENTJ