UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 44 / No. 4 / Published : 2011-12

Order : 6, and page :192 - 195

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Original Article :

The effect of spirulina gel on fibroblast cell number after wound healing process

Author :

  1. Fitria Rahmitasari *1
  2. Wisnu Setyari J *2
  3. Ester Arijani Rachmat*3
  1. Student, Faculty of Dentistry, Airlangga University, Surabaya - Indonesia
  2. Department of Oral Biology Faculty of Dentistry, Airlangga University, Surabaya - Indonesia
  3. Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta-Indonesia

Abstract :

Background: Wound healing treatment after tooth extraction should be an important consideration due to mouth discomfort and pain. Spirulina (blue green algae) consists of C-phycocyanin, b–carotenoids, vitamin E, zinc, some other trace elements and natural phytochemical which are believed to act as antioxidant and takes part in wound healing process. Purpose: The purpose of this study was to examine the effect of spirulina gel on fibroblast cell number after wound healing process. Methods: Twenty eight males guinea pig are devided into four group, 7 guinea pig each. They are control group and treatment group which is given 0%, 3%, 6%, and 12% spirulina gel. After tooth extraction, histopathological evaluation was done to count fibroblast cell. The data was analyzed by One-Way ANOVA and Tukey HSD. Results: The research has proven the relation between the increased growth of fibroblast cell and spirulina gel application. The higher the doses, the more cell growth. Hence, there has been significant different (p < 0.05) among groups. Conclusion: Spirulina gel increases the number of fibroblast in wound after tooth extraction and 12% spirulina gel has the most potential ability.

Keyword :

Spirulina gel, fibroblast cell number, wound healing,


References :

Romay CH,(2003) CPhycocyanin: A biliprotein with antioxidant, anti-inflammatory and neuroprotective effects. - : Current Protein and Peptide Science





Archive Article

Cover Media Content

Volume : 44 / No. : 4 / Pub. : 2011-12
  1. Betel Leaf Toothpastes Inhibit Dental Plaque Formation On Fixed Orthodontic Patients
  2. In Vivo Characterization Of Polymer Based Dental Cements
  3. Oral Rinse As A Potential Method To Culture Candida Isolate From Aids Patients
  4. In Vitro Effect Of Q-switched Nd:yag Laser Exposure On Morphology, Hydroxyapatite Composition And Microhardness Properties Of Human Dentin
  5. The Effectiveness Of Mimba Oil (azadirachta Indica A. Juss) Spray Disinfectant On Alginate Impression
  6. The Effect Of Spirulina Gel On Fibroblast Cell Number After Wound Healing Process
  7. The Difference Of Residual Monomer Levels Of Acrylic Resin With Various Polymerization Method
  8. Stimulation Of Osteoblast Activity By Induction Of Aloe Vera And Graft Combination
  9. Plaque Index Between Blind And Deaf Children After Dental Health Education
  10. The Difference Of Dental Anxiety Degree In Children Based On The Frequency Of Dental Appointment
  11. Volatile Sulphur Compounds Elimination: A New Insight In Periodontal Treatment
  12. Piperin And Piplartin As Natural Oral Anticancer Drug

Information DENTJ