UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 42 / No. 2 / Published : 2009-04

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Original Article :

The effect of watermelon frost on prostaglandin e2 (pge2) in inflamed pulp tissue (in vitro study)

Author :

  1. Dennis*1
  2. Trimurni Abidin*2
  1. Department of Conservative Dentistry
    Faculty of Dentistry, University of North Sumatera
    Medan - Indonesia

  2. Department of Conservative Dentistry
    Faculty of Dentistry, University of North Sumatera
    Medan - Indonesia

Abstract :

Background: Pulp inflammation can be marked by the increase of prostaglandin E2 (PGE2) level compared to normal pulp. The increase of PGE2 may lead to vasodilatation, increase of vascular permeability, pain and bone resorption. Watermelon frost has been well known in Chinese society for pain relief and inflammation in oral cavity and teeth. Purpose: The aim of this study was to investigate that watermelon frost can be used to decrease the PGE2 level. Method: 27 samples of pulp tissues used in this in-vitro study, were extirpated from the patients’ teeth with symptomatic irreversible pulpitis referred to clinic of Conservative Dentistry, RSPGM Faculty of Dentistry, USU. Trial materials were applied to 27 samples i.e. watermelon frost as a trial material and commercial watermelon frost and eugenol to observe their effect on PGE2. PGE2 level of each material was detected through ELISA method by measuring and comparing the absorbance reading of the wells of the samples against standards with a micro plate reader at W1=650nm and W2=490nm. Result: The result showed the biggest effect was found in the third group (eugenol), mean 4.6933, followed by the first group (watermelon frost as a trial material), mean 18,1578 then the second group (commercial watermelon frost), mean 82,2689. One-Way ANOVA revealed that there were significant differences among all trial materials (p

Keyword :

watermelon frost, PGE2, inflammation, pain ,


References :





Archive Article

Cover Media Content

Volume : 42 / No. : 2 / Pub. : 2009-06
  1. Diagnosis And Management Of Crohn’s Disease In Retarded Child
  2. Pseudomembranous Candidiasis In Patient Wearing Full Denture
  3. Cooperation Of Patient As Key Factor To Overcome Oral Habits
  4. Transformation Analysis Of Oral Epithelial Dysplasia To Cis And Scc By P53 Expression And Gene Mutations
  5. Aesthethic And Masticatory Rehabilitation On Post Mandibular Resection With Combination Of Hollow Obturator And Hybrid Prosthesis
  6. The Effect Of Watermelon Frost On Prostaglandin E2 (pge2) In Inflamed Pulp Tissue (in Vitro Study)
  7. Shear Bond Strength Between Porcelain And Nano Filler Composite Resin With Or Without 9% Hydrofluoric Acid Etching
  8. Screening Of Oral Premalignant Lesions In Smokers Using Toluidine Blue
  9. Biocompatibility Of Acrylic Resin On Bhk–21 Cell Line After Being Soaked In Sodium Hypochlorite
  10. The Aesthetic Treatment For Anterior Teeth With Lost Crown, By Endorestoration
  11. Prognostic Value Of Molecular Markers Of Oral Pre-malignant And Malignant Lesions

Information DENTJ