UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 41 / No. 1 / Published : 2008-01

Related with : Scholar   Yahoo!   Bing

Original Article :

The in vitro assessment of anti proliferation activity of crude diethyl ether extract of dendrophthoe species to myeloma culture cell

Author :

  1. Mochamad Lazuardi*1
  1. Veterinary Faculty Airlangga University
    Surabaya - Indonesia

Abstract :

Herb medicine have an active substances that can dissolved on polar, semi polar and non polar liquid extract. The methanol and ethyl acetate as a polar and semi polar extract liquid were used to study of herb medicine such as Dendrophthoe species. Diethyl ether as a non polar liquid extract was never use to study the Dendrophthoe species. The aim of this study was to investigate the anti proliferation activity of Dendrophthoe species to myeloma culture cells after extracted by non-polar extract solution (diethyl ether). The post test only control group design was used for this research. A thirty six of microtiterplates wells were used for myeloma culture cells in RPMI medium. The wells were devided placing in two groups: treatment groups and controls groups. Each three wells of six treatment subgroups added with 100 l of 1.1; 5.5; 11; 22; 33 and 44 g/ml crude diethyl ether extract series. A RPMI solution at similar method and volume were used as control substances. The cells were assessed by inverted microscope in 200x magnified two days after. The cells were quantified analyzed for anti proliferation activity by using 1:1 methylene blue solution. The results showed that started from 11.0 g/ml of crude diethyl ether extract of Dendrophthoe species have been anti proliferation abilities of myeloma culture cells (p0.05). In conclusion, actives substances of Dendrophthoe species where dissolved in non polar liquid as diethyl ether has anti proliferation activities to cancer cell in vitro.

Keyword :

cancer, herb medicine, myeloma, Dendrophthoe species, anti proliferation,


References :





Archive Article

Cover Media Content

Volume : 41 / No. : 1 / Pub. : 2008-03
  1. Three Dimensional Changes In Maxillary Complete Dentures Immersed In Water For Seven Days After Polymerization
  2. The In Vitro Assessment Of Anti Proliferation Activity Of Crude Diethyl Ether Extract Of Dendrophthoe Species To Myeloma Culture Cell
  3. Coen’s Ascending Ramus Fixator Use For Repositioning The Ascending Ramus During Mandible Reconstruction
  4. The Role Of Transforming Growth Factor Beta In Tertiary Dentinogenesis
  5. Morphological Changes Of Alveolar Bone Due To Orthodontic Movement Of Maxillary And Mandibulary Incisors
  6. The Effect Of Psidium Guajava Linn Leaf Extract On Candida Albicans Adherence And The Transversal Strength Of Acrylic Resin
  7. Side Effects Of Mercury In Dental Amalgam
  8. Pulp Tissue Vacuolization And Necrosis After Direct Pulp Capping With Calcium Hydroxide And Transforming Growth Factor-1
  9. Antimicrobial Effect Of Calcium Hydroxide As Endo Intracanal Dressing On Streptococcus Viridans
  10. Gingival Immunologic Defense Index: A New Indicator For Evaluating Dental Plaque Infection Risk In Allergic Children
  11. Expression Toll-like Receptors In The Oral Mucosal Of Patients With Recurrent Aphthous Stomatitis

Information DENTJ