UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 45 / No. 2 / Published : 2012-06

Order : 7, and page :93 - 96

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Original Article :

The increasing of enamel calcium level after casein phosphopeptide-amorphous calcium phosphate covering

Author :

  1. Widyasri Prananingrum*1
  2. Puguh Bayu Prabowo*2
  1. Department of Dental Material, Faculty of Dentistry, Hang Tuah University, Surabaya – Indonesia
  2. Department of Dental Material, Faculty of Dentistry, Hang Tuah University, Surabaya – Indonesia

Abstract :

Background: Caries process is characterized by the presence of demineralization. Demineralization is caused by organic acids as a result of carbohydrate substrate fermentation. Remineralization is a natural repair process for non-cavitated lesions. Remineralization occurs if there are Ca2+ and PO4 3- ions in sufficient quantities. Casein-amorphous calcium phosphate phosphopeptide (CPP-ACP) is a paste material containing milk protein (casein), that actually contains minerals, such as calcium and phosphate. The casein ability to stabilize calcium phosphate and enhance mineral solubility and bioavailability confers upon CPP potential to be biological delivery vehicles for calcium and phosphate. Purpose: The aim of this study was to determine the calcium levels in tooth enamel after being covered with CPP-ACP 2 times a day for 3, 14 and 28 days. Methods: Sample were bovine incisors of 3 year old cows divided into 4 groups, namely group I as control group, group II, III and IV as treatment groups covered with CPP-ACP 2 times a day. All of those teeth were then immersed in artificial saliva. Group II was immersed for 3 days, while group III was immersed for 14 days, and group IV was immersed for 28 days. One drop of CPP-ACP was used to cover the entire labial surface of teeth. The measurement of the calcium levels was then conducted by using titration method. All data were analyzed by One- Way ANOVA test with 5% degree of confidence. Results: The results showed significant difference of the calcium levels in tooth enamel of those groups after covered with CPP-ACP 2 times a day for 3, 14 and 28 days (p = 0.001). There is also significant difference of the calcium levels in tooth enamel of those treatment groups and the control group (p = 0.001). Conclusion: The calcium levels of tooth enamel are increased after covered with CPP-ACP 2 times a day for 3, 14 and 28 days.

Keyword :

Calcium, enamel, Casein phosphopeptide-amorphous calcium phosphate,


References :

Fejerskov O,(2008) Dental caries: The disease and its clinical management Australia : Blackwell Munksgaard





Archive Article

Cover Media Content

Volume : 45 / No. : 2 / Pub. : 2012-06
  1. The Importance Of Masticatory Functional Analysis In The Diagnostic Finding And Treatment Planning For Prosthodontic Rehabilitation
  2. The Management Of Chronic Traumatic Ulcer In Oral Cavity
  3. Simplified Digital Infra Red Photography: An Alternative Tool In Bitemark Forensic Investigation
  4. The Relation Between Salivary Siga Level And Caries Incidence In Down Syndrome Children
  5. Inhibition Of 10% Alpinia Galanga And Alpinia Purpurata Rhizome Extract On Candida Albicans Growth
  6. Pulpal Inflammation After Vital Tooth Bleaching With 38% Hydrogen Peroxide
  7. The Increasing Of Enamel Calcium Level After Casein Phosphopeptide-amorphous Calcium Phosphate Covering
  8. Cytotoxicity Of Betel Leaf (piper Betel L.) Against Primary Culture Of Chicken Embryo Fibroblast And Its Effects On The Production Of Proinflammatory Cytokines By Human Peripheral Blood Mononuclear Cells
  9. Deoxypyridinoline Level In Gingival Crevicular Fluid As Alveolar Bone Loss Biomarker In Periodontal Disease
  10. Craniofacial Morphology Of Children With Complete Unilateral Cleft Lip And Palate Following Labioplasty And Palatoplasty
  11. Seroprevalence Of Herpes Simplex Virus Types 1 And 2 And Their Association With Cd4 Count Among Hiv-positive Patients

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