Dental Journal (Majalah Kedokteran Gigi)
ISSN 1978-3728
Vol. 45 / No. 4 / Published : 2012-12
Order : 10, and page :228 - 233
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Original Article :
The increasing of fibroblast growth factor 2, osteocalcin, and osteoblast due to the induction of the combination of aloe vera and 2% xenograft concelous bovine
Author :
- Utari Kresnoadi*1
- Dosen Fakultas Kedokteran Gigi
Abstract :
Background:To make a successfull denture prominent ridge is needed, preservation on tooth extraction socket is needed in order to prevent alveol bone resorption caused by revocation trauma. An innovative modification of the material empirically suspected to be able reduce inflammation caused by the revocation trauma is a combination of Aloe vera and xenograft concelous bovine (XCB) and Aloe vera is a biogenic stimulator and accelerating the growth of alveolar ridge bone after tooth extraction. Purpose:The research was aimed to determine of the increasing alveol bone formation by inducing the combination of Aloe vera and 2% xenograft concelous bovine. Methods:To address the problems, the combination of Aloe vera and xenograft concelous bovine was induced into the tooth extraction sockets of Cavia cabayas which devided on 8 groups. Groups control, filled with XCB, Aloe vera and Aloe vera and XCB combination, at 7 days and 30 days after extraction. Afterwards, immunohistochemical examination was conducted to examine the expressions of FGF-2 and osteocalcin, as the product of the growth of osteoblasts. Results:There were significantly increases expression of FGF-2 and osteocalcyn on group which filled with XCB, Aloe vera and combined Aloe vera and XCB. Conclusion:It may be concluded that the induction of the combination of Aloe vera and xenograft concelous bovine into the tooth sockets can enhance the growth expressions of FGF-2 and osteocalcin as the product of osteoblasts, thus, the growth of alveolar bone was increased.
Keyword :
ibroblast growth factor 2, osteocalcin, osteoblast, alveolar bone, combination of Aloe vera and graft,
References :
Ariyani E,(2008) The use 90 % Aloe verafrezze dryiing as modulator of collagen density in exctraction socket of incisivus Cavia cabaya Surabaya : Dent J (Maj. Ked. Gigi)
Archive Article
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Volume : 45 / No. : 4 / Pub. : 2012-12 |
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