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Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 45 / No. 4 / Published : 2012-12

Order : 10, and page :228 - 233

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Original Article :

The increasing of fibroblast growth factor 2, osteocalcin, and osteoblast due to the induction of the combination of aloe vera and 2% xenograft concelous bovine

Author :

  1. Utari Kresnoadi*1
  1. Dosen Fakultas Kedokteran Gigi

Abstract :

Background:To make a successfull denture prominent ridge is needed, preservation on tooth extraction socket is needed in order to prevent alveol bone resorption caused by revocation trauma. An innovative modification of the material empirically suspected to be  able reduce inflammation caused by the revocation trauma is a combination of Aloe vera and xenograft concelous bovine (XCB) and  Aloe vera is a biogenic stimulator and accelerating the growth of alveolar ridge bone after tooth extraction. Purpose:The research was  aimed to determine of the increasing alveol bone formation by inducing the combination of Aloe vera and 2% xenograft concelous bovine.  Methods:To address the problems, the combination of Aloe vera and xenograft concelous bovine was induced into the tooth extraction  sockets of Cavia cabayas which devided on 8 groups. Groups control, filled with XCB, Aloe vera and Aloe vera and XCB combination,  at 7 days and 30 days after extraction. Afterwards, immunohistochemical examination was conducted to examine the expressions of  FGF-2 and osteocalcin, as the product of the growth of osteoblasts. Results:There were significantly increases expression of FGF-2 and osteocalcyn on group which filled with XCB, Aloe vera and combined Aloe vera and XCB. Conclusion:It may be concluded that  the induction of the combination of Aloe vera and xenograft concelous bovine into the tooth sockets can enhance the growth expressions  of FGF-2 and osteocalcin as the product of osteoblasts, thus, the growth of alveolar bone was increased.

Keyword :

ibroblast growth factor 2, osteocalcin, osteoblast, alveolar bone, combination of Aloe vera and graft,


References :

Ariyani E,(2008) The use 90 % Aloe verafrezze dryiing as modulator of collagen density in exctraction socket of incisivus Cavia cabaya Surabaya : Dent J (Maj. Ked. Gigi)





Archive Article

Cover Media Content

Volume : 45 / No. : 4 / Pub. : 2012-12
  1. The Role Of Actinobacillus Actinomycetemcomitans Fimbrial Adhesin On Mmp-8 Activity In Aggressive Periodontitis Pathogenesis
  2. Aesthetic Treatment On Anterior Teeth Crown Fracture Caused By Dental Trauma
  3. Molecular Characterization Of Interleukin-1a (+4845) Gtgene In Aggresive Periodontitis Patients
  4. Antitumor Activity Of Intratumoral Injection Of Pcdna3.1-p27kip1mt Followed By In Vivo Electroporation In A Malignant Burkitt’s Lymphoma Cell Xenograft
  5. The Effect Of Nickel As A Nickel Chromium Restoration Corrosion Product On Gingival Fibroblast Through Analysis Of Bcl-2
  6. Inhibition Of Dental Plaque Formation By Toothpaste Containing Propolis
  7. Inhibition Effect Of Cashew Stem Bark Extract (anacardium Occidentale L.) On The Inhibition Of Biofilm Formation Of Streptococcus Sanguinis
  8. Antibacterial Efficacy Of Salvadora Persicaas A Cleansing Teeth Towards Streptococcus Mutansand Lactobacilli Colonies
  9. Pomegranate Juice As An Ideal Mouthrinse For Fixed Orthodontic Patients
  10. The Increasing Of Fibroblast Growth Factor 2, Osteocalcin, And Osteoblast Due To The Induction Of The Combination Of Aloe Vera And 2% Xenograft Concelous Bovine
  11. The Ph Changes Of Artificial Saliva After Interaction With Oral Ph Changes Of Artificial Saliva After Interaction With Oral Changes Of Artificial Saliva After Interaction With Oral Micropathogen