UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 41 / No. 4 / Published : 2008-10

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Original Article :

The relation of periodontal diseases to systemic diseases

Author :

  1. Melanie Sadono Djamil*1
  2. Boedi Oetomo Roeslan*2
  1. Biochemistry and Oral Biology Department, Faculty of Dentistry, Trisakti University
  2. Lecturer, Immunopathology and Molecular Biology, Postrgaduate Program, Trisakti University

Abstract :

Background: The relationship between systemic disorders and periodontal disease has been studied extensively. With few exceptions, it is more accurate to consider systemic diseases to be contributing factors in the pathogenesis of periodontal disease rather than the primary etiologic factors. The development of periodontal disease cannot be separated from the weakening of immunologic and immunopathological responses. Periodontal disease may enhance susceptibility to certain systemic diseases in several ways. Lipopolysaccharide (LPS) and Gram-positive bacteria in the biofilm and proinflammatory cytokines produced from inflamed periodontal tissues may enter the circulation system causing the development of certain systemic diseases. On the other hand, through immunologic mediators, certain systemic disease may enhance susceptibility to periodontal disease caused by the decrease of immune responses and the increase of proinflammatory cytokines. Purpose: The Purpose of this article is to review the immunologic aspect of two way relationship between systemic diseases and periodontal diseases. Review: This review studied the relationship between general health status, systemic diseases, and periodontal diseases through immunopathological responses and the weakening of the immune system in the periodontal tissue. Conclusion: there is a two-way relationship between periodontal diseases and systemic diseases.

Keyword :

periodontal disease, systemic diseases, immunological, two-way relationship,


References :





Archive Article

Cover Media Content

Volume : 41 / No. : 4 / Pub. : 2009-12
  1. Effect Of Oxygen Hyperbaric Therapy On Malondialdehyde Levels In Saliva Of Periodontitis Patients With Type 2 Diabetes Mellitus
  2. Reducing Allergic Symptoms Through Eliminating Subgingival Plaque
  3. The Role Of Dentists On Medically Compromised Children’s Oral And Dental Prophylaxis In Hospital
  4. The Surface Roughness Difference Between Microhybrid And Polycrystalline Composites After Polishing
  5. The Relation Of Periodontal Diseases To Systemic Diseases
  6. Delayed Bracket Placement In Orthodontic Treatment
  7. Complex Aesthetic Treatment On Anterior Maxillary Teeth With Malposition
  8. Stimulation Of Type I Collagen Activity In Healing Of Pulp Perforation
  9. The Combination Of Sodium Perborate And Water As Intracoronal Teeth Bleaching Agent
  10. Bootstrap Study To Estimate Linear Regression Parameter (application In The Study On The Effect Of Oral Hygiene On Dental Caries)
  11. Immunodetection Of Rasp21 And C-myc Oncogenes In Oral Mucosal Swab Preparation From Clove Cigarette Smokers

Information DENTJ